AI Article Synopsis
- Natural materials have irregular structures that provide key functions like protection and stress modulation, which is essential for maintaining balance in biological systems and healing tissues.
- A new computational framework was developed to optimize the arrangement of basic building blocks, creating irregular materials that effectively control stress distribution across different areas and conditions, similar to natural materials.
- The effectiveness of these materials was confirmed through 3D printed prototypes, showing promise for use in orthopedic applications, such as supporting bone repair in femur restoration.
Article Abstract
Natural materials typically exhibit irregular and non-periodic architectures, endowing them with compelling functionalities such as body protection, camouflage, and mechanical stress modulation. Among these functionalities, mechanical stress modulation is crucial for homeostasis regulation and tissue remodeling. Here, we uncover the relationship between stress modulation functionality and the irregularity of bio-inspired architected materials by a generative computational framework. This framework optimizes the spatial distribution of a limited set of basic building blocks and uses these blocks to assemble irregular materials with heterogeneous, disordered microstructures. Despite being irregular and non-periodic, the assembled materials display spatially varying properties that precisely modulate stress distribution towards target values in various control regions and load cases, echoing the robust stress modulation capability of natural materials. The performance of the generated irregular architected materials is experimentally validated with 3D printed physical samples - a good agreement with target stress distribution is observed. Owing to its capability to redirect loads while keeping a proper amount of stress to stimulate bone repair, we demonstrate the potential application of the stress-programmable architected materials as support in orthopedic femur restoration.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11109255 | PMC |
| http://dx.doi.org/10.1038/s41467-024-47831-2 | DOI Listing |
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