An infrared squaraine dye was utilized to detect Cu in solvents based on H-aggregates of squaraine dye. H-aggregates are a type of aggregation with enhanced photophysical properties compared to monomers. In the presence of a Ca solution, F-Cl offers exceptional H-aggregators that can be transformed into monomers by adding Cu. Furthermore, this mode successfully demonstrated fluorescence changes in HeLa cells cultured in vitro after the addition of Ca or Cu. A highly specific detection of Cu was achieved using this transformation mode.
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http://dx.doi.org/10.1177/00037028241254391 | DOI Listing |
In this study, we present a protecting group photocleavage method to investigate both covalent and noncovalent interactions between a squaraine dye (PSq) and Bovine Serum Albumin (BSA). This approach allows for the photoinduced activation and deactivation of PSq fluorescence, providing valuable insights into the dual-mode interaction of the dye with the protein.
View Article and Find Full Text PDFAnal Sci
December 2024
NHC Key Laboratory for Engineering Control of Dust Hazard, National Center for Occupational Safety and Healthy, NHC, Beijing, 102308, China.
We synthesized a squaraine dye (F-0) to develop a method for detecting pyrophosphate (PPi) and alkaline phosphatase (ALP) by modulating the fluorescence of F-0. The fluorescence intensity of the F-0 system was quenched upon the addition of Cu ions; however, it was restored when PPi was introduced due to the formation of a complex between PPi and Cu. Since ALP can hydrolyze PPi, the fluorescence of the system was quenched again upon the addition of ALP.
View Article and Find Full Text PDFMolecules
October 2024
Department of Applied Science and Engineering, Fukui University of Technology, Fukui 910-8505, Japan.
We developed dye-sensitized solar cells (DSSCs) using 1,5-carboxy-2-[[3-[(2,3-dihydro-1,1-dimethyl-3-ethyl-1H-benzo[e]indol-2-ylidene)methyl]-2-hydroxy-4-oxo-2-cyclobuten-1-ylidene]methyl]-3,3-dimethyl-1-octyl-3H-indolium and 1,3,3-trimethyl indolino-6'-nitrobenzopyrylospiran. The DSSCs incorporate photochromic molecules to regulate photoelectric conversion properties. We irradiated photoelectrodes adsorbed with SQ2/SPNO using both UV and visible light and observed the color changes in these photoelectrodes.
View Article and Find Full Text PDFBiosensors (Basel)
September 2024
Graduate School of Life Science and System Engineering, Kyushu Institute of Technology, 2-4 Hibikino, Wakamatsu-Ku, Kitakyushu-Shi, Fukuoka 808-0196, Japan.
Trypsin enzyme has gained recognition as a potential biomarker in several tumors, such as colorectal, gastric, and pancreatic cancer, highlighting its importance in disease diagnosis. In response to the demand for rapid, cost-effective, and real-time detection methods, we present an innovative strategy utilizing the design and synthesis of NIR-sensitive dye-peptide conjugate () for the sensitive and selective monitoring of trypsin activity by fluorescence ON/OFF sensing. The current research deals with the design and synthesis of three unsymmetrical squaraine dyes , , and along with a dye-peptide conjugate as a trypsin-specific probe followed by their photophysical characterizations.
View Article and Find Full Text PDFCommun Chem
October 2024
Institut für Chemie und Biochemie, Freie Universität Berlin, Arnimallee 20, 14195, Berlin, Germany.
In nature, molecular environments in proteins can sterically protect and stabilize reactive species such as organic radicals through non-covalent interactions. Here, we report a near-infrared fluorescent rotaxane in which the stabilization of a chemically labile squaraine fluorophore by the coordination of a tetralactam macrocycle can be controlled chemically and electrochemically. The rotaxane can be switched between two co-conformations in which the wheel either stabilizes or exposes the fluorophore.
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