An infrared squaraine dye was utilized to detect Cu in solvents based on H-aggregates of squaraine dye. H-aggregates are a type of aggregation with enhanced photophysical properties compared to monomers. In the presence of a Ca solution, F-Cl offers exceptional H-aggregators that can be transformed into monomers by adding Cu. Furthermore, this mode successfully demonstrated fluorescence changes in HeLa cells cultured in vitro after the addition of Ca or Cu. A highly specific detection of Cu was achieved using this transformation mode.

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http://dx.doi.org/10.1177/00037028241254391DOI Listing

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