Performing an action to initiate a consequence in the environment triggers the perceptual illusion of temporal binding. This phenomenon entails that actions and following effects are perceived to occur closer in time than they do outside the action-effect relationship. Here we ask whether temporal binding can be explained in terms of multisensory integration, by assuming either multisensory fusion or partial integration of the two events. We gathered two datasets featuring a wide range of action-effect delays as a key factor influencing integration. We then tested the fit of a computational model for multisensory integration, the statistically optimal cue integration (SOCI) model. Indeed, qualitative aspects of the data on a group-level followed the principles of a multisensory account. By contrast, quantitative evidence from a comprehensive model evaluation indicated that temporal binding cannot be reduced to multisensory integration. Rather, multisensory integration should be seen as one of several component processes underlying temporal binding on an individual level.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/j.cogpsych.2024.101662 | DOI Listing |
New Phytol
January 2025
Frontiers Science Center for Molecular Design Breeding (MOE), Department of Ornamental Horticulture, College of Horticulture, China Agricultural University, Beijing, 100193, China.
Temporal decline in microRNA miR156 expression is crucial for the transition to, and maintenance of, the adult phase and flowering competence in flowering plants. However, the molecular mechanisms underlying the temporal regulation of miR156 reduction remain largely unknown. Here, we investigated the epigenetic mechanism regulating the temporal silencing of cin-MIR156 in wild chrysanthemum (Chrysanthemum indicum), focusing on the role of the lysine-specific demethylase CiLDL1 and the nuclear factor Y complex.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Rheumatology and Immunology, Shanxi Provincial People's Hospital, Taiyuan, 030012, China.
Previous research suggests mitochondrial apoptosis alleviates rheumatoid arthritis (RA), but the role of mitochondrial apoptosis-related genes (MARGs) is unclear. Urgent exploration of RA-related mitochondrial apoptosis biomarkers is needed. Gene Expression Ontology (GEO)-derived RA datasets were used to identify differentially expressed genes (DEGs) compared to normal controls, intersected with MARGs to obtain differentially expressed mitochondrial apoptosis-related genes (DE-MARGs).
View Article and Find Full Text PDFJ Nucl Med
January 2025
Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts;
Spinal cord injuries (SCIs) often lead to lifelong disability. Among the various types of injuries, incomplete and discomplete injuries, where some axons remain intact, offer potential for recovery. However, demyelination of these spared axons can worsen disability.
View Article and Find Full Text PDFNat Commun
January 2025
Department of Clinical and Experimental Epilepsy, Queen Square Institute of Neurology, UCL, London, WC1N 3BG, UK.
Approximately 40% of individuals undergoing anterior temporal lobe resection for temporal lobe epilepsy experience episodic memory decline. There has been a focus on early memory network changes; longer-term plasticity and its impact on memory function are unclear. Our study investigates neural mechanisms of memory recovery and network plasticity over nearly a decade post-surgery.
View Article and Find Full Text PDFBiochim Biophys Acta Gen Subj
January 2025
Faculty of Life and Environmental Sciences, University of Yamanashi, 4-4-37 Takeda, Kofu, Yamanashi 400-8510, Japan.
Background: Postprandial hyperglycemia induces expression of inflammatory cytokines including tumor necrosis factor (TNF), which promotes the onset of type 2 diabetes and cardiovascular diseases. In this study, we investigated whether a transient high-glucose culture enhanced sustained expression of TNF, or whether the induction is associated with histone acetylation, and bromodomain protein containing protein 4 (BRD4), which binds acetylated histone, in human juvenile macrophage-like THP-1 cells.
Methods: THP-1 cells were cultured in medium with high-glucose in the presence or absence of (+)-JQ1, an inhibitor of bromodomain and extra-terminal domain family, for 24 h (day 0).
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!