Key Clinical Message: Atrial fibrillation is closely associated with thrombotic events. In non-valvular atrial fibrillation, 90% of thrombi are formed by the left atrial appendage. Left atrial appendage occlusion (LAAC) can effectively prevent the detachment of left atrial appendage thrombus during atrial fibrillation, thereby reducing the risk of long-term disability or death caused by thromboembolic events. However, the identification and management of complications in LAAC are also very important.
Abstract: The efficacy and safety of left atrial appendage occlusion (LAAC) in preventing non-valvular atrial fibrillation stroke have been confirmed by multiple randomized controlled and registered studies, and have been recommended by several guidelines for stroke prevention in patients with atrial fibrillation at high-risk of stroke. We reported an 80-year-old male patient with persistent atrial fibrillation. The patient underwent left atrial appendage closure surgery due to high risk of embolism and bleeding. On the second day after surgery, echocardiography showed displacement of the left atrial appendage occluder. Immediately perform removal of left atrial appendage occlude and left atrial appendage occlusion on the same day, and the patient was discharged on the fifth day after surgery without any special circumstances. This case demonstrates the feasibility and important clinical significance of using interventional surgery to remove the left atrial appendage occluder after displacement in clinical practice.
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http://dx.doi.org/10.1002/ccr3.8915 | DOI Listing |
Circ J
January 2025
Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine.
Background: Fatal arrhythmic events (FAEs), such as sudden cardiac death (SCD) and fatal ventricular arrhythmias, are a devastating complication in patients with coronary artery disease (CAD). Therefore, in this study we aimed to assess the incidence of FAEs in more recent Japanese patients with CAD and to examine whether risk stratification of FAEs can still be feasible using the left ventricular ejection fraction (LVEF).
Methods And Results: In the CREDO Kyoto PCI/CABG registry cohorts-2 and -3, there were 25,843 patients with LVEF data who received a first coronary revascularization (LVEF ≤35% group: N=1,671, 35%
Heart Rhythm
January 2025
Division of Cardiology, Department of Medicine, Nihon University School of Medicine Tokyo Japan. Electronic address:
Background: Pulsed field ablation (PFA) for paroxysmal atrial fibrillation (AF) has been gaining worldwide acceptance due to its efficacy and safety. A variable loop circular catheter (VLCC, VARIPULSE, Biosense Webster, Inc.) for PFA, recently launched in Japan, includes a Tissue Proximity Indication (TPI) feature to monitor catheter-tissue contact via impedance.
View Article and Find Full Text PDFHeart Rhythm
January 2025
Cardioangiologisches Centrum Bethanien, AGAPLESION Markus Krankenhaus, Academic Teaching Hospital of the Goethe University, Frankfurt, Germany.
Med Image Anal
January 2025
School of Biomedical Engineering and Imaging Sciences, King's College London, UK. Electronic address:
Atrial fibrillation (AF), impacting nearly 50 million individuals globally, is a major contributor to ischaemic strokes, predominantly originating from the left atrial appendage (LAA). Current clinical scores like CHA₂DS₂-VASc, while useful, provide limited insight into the pro-thrombotic mechanisms of Virchow's triad-blood stasis, endothelial damage, and hypercoagulability. This study leverages biophysical computational modelling to deepen our understanding of thrombogenesis in AF patients.
View Article and Find Full Text PDFPort J Card Thorac Vasc Surg
January 2025
Thoracic Surgery Department, Pulido Valente Hospital, CHULN, Lisbon, Portugal.
Introduction: Complete radical resection is crucial for successfully treating thymic carcinomas. However, when the invasion of the great vessels or the heart in Masaoka III and IV stages occurs, the management poses more challenges. The R0 resection often requires neoadjuvant treatment.
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