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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11101802PMC
http://dx.doi.org/10.1016/j.ekir.2024.01.062DOI Listing

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Article Synopsis
  • Chronic kidney disease (CKD) is linked to higher risks of heart issues, prompting a study to investigate cardiac abnormalities at different CKD stages.
  • The study included 356 non-dialysis CKD patients, with most in stages III and IV, and assessed various health metrics along with detailed heart evaluations.
  • Results showed that as kidney disease progressed, heart issues like left ventricular hypertrophy and diastolic dysfunction worsened significantly, indicating a strong relationship between CKD severity and heart health.
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Heart failure (HF) is characterized by the activation of adverse neurohormonal systems and a high mortality rate. Noteworthy, HF is a well-known complication of chronic kidney disease (CKD), especially in end-stage kidney disease (ESKD), where dialysis patients are seven to eight times more likely to encounter cardiac arrest than the general population. Therefore, it is important to develop efficient treatments to improve cardiac function in dialysis patients and eventually reduce the cardiovascular death toll.

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Background: Patients on hemodialysis (HD) are prone to various cardiovascular complications. Two-dimensional speckle tracking echocardiography (2D STE) is an innovative technique for early myocardial dysfunction detection, even with normal ejection fraction (EF).

Objective: We aim to detect left ventricle (LV) dysfunction in regular hemodialysis patients using 2D STE compared to traditional echocardiography.

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Article Synopsis
  • Infective endocarditis (IE) is a serious heart infection that can occur even in patients without common risk factors, as shown in a case involving a 30-year-old male on hemodialysis.
  • The patient's infection was caused by a specific bacterium, leading to a diagnosis that was unfortunately delayed until significant damage to the mitral valve had occurred.
  • Despite treatment efforts, including valve replacement, the patient’s condition deteriorated, highlighting the need for rapid diagnosis and intervention in suspected IE cases, regardless of traditional risk factors.
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Background: Despite clinical practice guidelines prioritizing cardiorenal risk reduction, national trends in diabetes outcomes, particularly in rural communities, do not mirror the benefits seen in clinical trials with emerging therapeutics and technologies.

Objective: Project ECHO supports implementation of guidelines in under-resourced areas through virtual communities of practice, sharing of best practices, and case-based learning. We hypothesized that diabetes outcomes of patients treated by ECHO-trained primary care providers (PCPs) would be similar to those of patients treated by specialists at an academic medical center.

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