Objective: The aim of this study is to evaluate the etiological profile and antimicrobial resistance in breast abscess cultures from patients from the community, treated at a public hospital located in Porto Alegre, Brazil.
Methods: This is an retrospective cross-sectional study that evaluated the medical records of patients with bacterial isolates in breast abscess secretion cultures and their antibiograms, from January 2010 to August 2022.
Results: Based on 129 positive cultures from women from the community diagnosed with breast abscesses and treated at Fêmina Hospital, 99 (76.7%) of the patients had positive cultures for , 91 (92%) of which were cases of . Regarding the resistance profile of , 32% of the strains were resistant to clindamycin, 26% to oxacillin and 5% to trimethoprim-sulfamethoxazole. The antimicrobials vancomycin, linezolid and tigecycline did not show resistance for .
Conclusion: was the most common pathogen found in the breast abscess isolates during the study period. Oxacillin remains a good option for hospitalized patients. The use of sulfamethoxazole plus trimethoprim should be considered as a good option for use at home, due to its low bacterial resistance, effectiveness and low cost.
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http://dx.doi.org/10.61622/rbgo/2024rbgo34 | DOI Listing |
Photodiagnosis Photodyn Ther
January 2025
Department of Radiation Oncology, The Third Affiliated Hospital of Shandong First Medical University (Affiliated Hospital of Shandong Academy of Medical Sciences), Jinan, Shandong, China. Electronic address:
Background: Cholangiocarcinoma is a rare but highly fatal malignancy; numerous studies have demonstrated promising outcomes and survival rates associated with adjuvant photodynamic therapy (PDT) in the palliative treatment of cholangiocarcinoma.
Objective: To systematically evaluate the existing meta-analyses on PDT for cholangiocarcinoma, assessing evidence quality and strength while performing updated meta-analyses to refine survival outcomes.
Methods: PubMed, EMBASE, Cochrane Library, and Web of Science were systematically searched up to September 18, 2024, to identify meta-analyses and clinical studies on PDT in patients with cholangiocarcinoma.
Acad Radiol
January 2025
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing 100010, PR China (M.W., Y.L., D.Z., N.F., Y.W., M.L., H.Z.).
Rationale And Objectives: To summarize the clinical features and ultrasonic characteristics of patients with cystic neutrophilic granulomatous mastitis (CNGM), and to enhance the understanding of CNGM in clinical practice.
Materials And Methods: This study retrospectively analyzed the demographic data, clinical symptoms, and ultrasonic characteristics of 141 patients diagnosed with CNGM through pathological examination. This study was approved by the Medical Ethical Committee of Beijing Hospital of Traditional Chinese Medicine (2023BL02-054-01).
Cureus
November 2024
Surgery, Arabian Gulf University, Manama, BHR.
Granulomatous mastitis is a chronic inflammation of the breast, mostly of unknown etiology. The treatment would be definitive if the causative organism were isolated. It is characterized histologically by granulomas, formed mostly by polymorph nuclear neutrophils and central necrosis.
View Article and Find Full Text PDFExpert Opin Drug Saf
December 2024
Department of Pharmacy, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Background: Ustekinumab is a fully human interleukin-12/23 (p40) inhibitor used to treat immune-mediated diseases. However, the limitations of clinical trials and the expanding target population necessitate an update on the ustekinumab-associated adverse events (AEs). We conducted signal mining for ustekinumab-related AEs using the United States Food and Drug Administration Adverse Event Reporting System (FAERS).
View Article and Find Full Text PDFJ Breast Imaging
December 2024
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Cystic neutrophilic granulomatous mastitis (CNGM) is a rare type of granulomatous lobular mastitis (GLM) with a distinct histologic pattern characterized on histopathology by clear lipid vacuoles lined by peripheral neutrophils ("suppurative lipogranulomas"), often containing gram-positive bacilli and strongly associated with Corynebacterial infection (in particular, Corynebacterium kroppenstedtii). Cystic neutrophilic granulomatous mastitis has a distinct histopathologic appearance, but the imaging appearance is less well described and has been limited to case reports and small case series published primarily in pathology literature. Mammographic findings of CNGM include focal asymmetry, skin thickening, and irregular or oval masses.
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