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Pilot Study of Cerebral Hemodynamics in Depressive Patient Under Electroconvulsive Therapy.
Neuropsychiatr Dis Treat
December 2024
Research Center of Educational Neuroscience, School of Educational Science, Huazhong University of Science and Technology, Wuhan City, Hubei Province, People's Republic of China.
Background: Major depressive disorder (MDD) poses a significant treatment challenge, with some patients unresponsive to conventional therapies. Electroconvulsive therapy (ECT) can be effective but its mechanisms are not fully understood. This study employs functional Near-Infrared Spectroscopy (fNIRS) to explore the neurobiological changes induced by ECT in A MDD patient, aiming to shed light on its therapeutic effects.
View Article and Find Full Text PDFInvestigating Anxiety's Impact on Seizure Quality in Electroconvulsive Therapy: A Prospective Observational Study.
J ECT
December 2024
From the Département d'Anesthésie et Réanimation.
Background: Electroconvulsive therapy (ECT) is a medical procedure for treating severe depression and other mental health disorders, with anesthesia management being crucial for patient safety. Despite extensive research on factors influencing seizure quality during ECT, the impact of pre-ECT anxiety remains insufficiently explored.
Methods: This prospective observational study aimed to investigate the influence of pre-ECT anxiety, as measured by the Amsterdam Preoperative Anxiety and Information Scale, on electroencephalogram ictal characteristics during ECT and to explore anesthesia-related factors that may enhance seizure quality.
Use of Cholinesterase Inhibitors for Treatment and Prevention of Cognitive Adverse Effects of Electroconvulsive Therapy: A Systematic Review.
J ECT
December 2024
Pharmacy Service, Durham VA Health Care System, Durham, NC.
Although electroconvulsive therapy (ECT) is effective for treating depression, schizophrenia, and mania, cognitive adverse effects may limit use. One possible mechanism for these effects includes cholinergic transmission alterations, supporting potential use of cholinesterase inhibitors for prevention and treatment of these cognitive deficits. The objective of this review is to determine efficacy and safety of cholinesterase inhibitors clinically used for dementia in reducing ECT cognitive adverse effects.
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