Non-invasive electrical brain stimulation modulates human conscious perception of mental representation.

Neuroimage

Institute of Brain and Cognitive Engineering, Korea University, Seoul 02841, South Korea; BK21 Four Institute of Precision Public Health, Korea University, Seoul 02841, South Korea; Department of Brain and Cognitive Engineering, Korea University, Seoul 02841, South Korea. Electronic address:

Published: July 2024

Mental representation is a key concept in cognitive science; nevertheless, its neural foundations remain elusive. We employed non-invasive electrical brain stimulation and functional magnetic resonance imaging to address this. During this process, participants perceived flickering red and green visual stimuli, discerning them either as distinct, non-fused colours or as a mentally generated, fused colour (orange). The application of transcranial alternating current stimulation to the medial prefrontal region (a key node of the default-mode network) suppressed haemodynamic activation in higher-order subthalamic and central executive networks associated with the perception of fused colours. This implies that higher-order thalamocortical and default-mode networks are crucial in humans' conscious perception of mental representation.

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http://dx.doi.org/10.1016/j.neuroimage.2024.120647DOI Listing

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