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"Pardon My Language": The Curious Case of a Bloody Sandwich and the John Cunningham Virus Reactivation in the Era of Immunomodulatory Drugs.
Cureus
October 2024
Department of Family and Community Medicine, Creighton University School of Medicine, Phoenix, USA.
Progressive multifocal leukoencephalopathy (PML) is a rare diagnosis associated with high mortality in different clinical settings. PML has been attributed to the reactivation of the John Cunningham (JC) virus (JCV). JCV typically affects patients with HIV/AIDS, solid organ and hematological malignancies, and those under treatment with immunomodulatory drugs (IMiDs) like pomalidomide.
View Article and Find Full Text PDFArticle Synopsis
- The ASFA Attending Physician Subcommittee reviewed 2023 apheresis literature and selected the top 10 seminal articles in the field.
- They focused on four main topics: donor apheresis, therapeutic apheresis, education, and cellular therapy, using PubMed and OVID for research.
- The chosen articles met key criteria such as novel findings, practice-changing results, and relevance to current clinical practice, while excluding case reports, reviews, and meta-analyses.
Why Do You Focus on the Acetabular Labral Tear? You Can't See the Forest for the Trees.
Arthroscopy
November 2024
Department of Orthopaedic Surgery & Rehabilitation, Texas Tech University Health Sciences Center, Lubbock, Texas; Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
The advent of higher-quality imaging has brought increased attention to the understanding and implications of commonly observed hip morphology and pathology. Many patients and even physicians like to focus on the presence of an acetabular labral tear when one is present on magnetic resonance imaging, despite the limitations of magnetic resonance imaging in identifying labral tears. Furthermore, recent studies have shown normal variations of the acetabular labrum, as well as a high prevalence of labral tears in both symptomatic and asymptomatic individuals.
View Article and Find Full Text PDFSARS-CoV-2 seroprevalence and associated factors among outpatient attendees at health facilities in different provinces in Chad.
BMC Infect Dis
November 2024
Faculty of Human Health Sciences, N'Djamena University, N'Djamena, Chad.
Background: Chad with 7,698 confirmed cases of infection and 194 deaths since the beginning of the COVID-19 pandemic, is one of the African countries with the lowest reported case numbers. However, this figure likely underestimates the true spread of the virus due to the low rate of diagnosis. The high rate of asymptomatic infections reflects the reality of SARS-CoV-2 transmission in Chad.
View Article and Find Full Text PDFNurse Burnout and Patient Safety, Satisfaction, and Quality of Care: A Systematic Review and Meta-Analysis.
JAMA Netw Open
November 2024
School of Medicine, Stanford University, Stanford, California.
Importance: Occupational burnout syndrome is characterized by emotional exhaustion, depersonalization, and a diminished sense of personal accomplishment and is prevalent among nurses. Although previous meta-analyses have explored the correlates of nurse burnout, none have estimated their association with health care quality and safety and patient morbidity and mortality.
Objective: To evaluate the magnitude and moderators of the association between nurse burnout and patient safety, patient satisfaction, and quality of care.
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