Background: A maternal mortality ratio is a sensitive indicator when comparing the overall maternal health between countries and its very high figure indicates the failure of maternal healthcare efforts. Cambodia, Laos, Myanmar, and Vietnam-CLMV countries are the low-income countries of the South-East Asia region where their maternal mortality ratios are disproportionately high. This systematic review aimed to summarize all possible factors influencing maternal mortality in CLMV countries.
Methods: This systematic review applied "The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Checklist (2020)", Three key phrases: "Maternal Mortality and Health Outcome", "Maternal Healthcare Interventions" and "CLMV Countries" were used for the literature search. 75 full-text papers were systematically selected from three databases (PubMed, Google Scholar and Hinari). Two stages of data analysis were descriptive analysis of the general information of the included papers and qualitative analysis of key findings.
Results: Poor family income, illiteracy, low education levels, living in poor households, and agricultural and unskilled manual job types of mothers contributed to insufficient antenatal care. Maternal factors like non-marital status and sex-associated work were highly associated with induced abortions while being rural women, ethnic minorities, poor maternal knowledge and attitudes, certain social and cultural beliefs and husbands' influences directly contributed to the limitations of maternal healthcare services. Maternal factors that made more contributions to poor maternal healthcare outcomes included lower quintiles of wealth index, maternal smoking and drinking behaviours, early and elderly age at marriage, over 35 years pregnancies, unfavourable birth history, gender-based violence experiences, multigravida and higher parity. Higher unmet needs and lower demands for maternal healthcare services occurred among women living far from healthcare facilities. Regarding the maternal healthcare workforce, the quality and number of healthcare providers, the development of healthcare infrastructures and human resource management policy appeared to be arguable. Concerning maternal healthcare service use, the provisions of mobile and outreach maternal healthcare services were inconvenient and limited.
Conclusion: Low utilization rates were due to several supply-side constraints. The results will advance knowledge about maternal healthcare and mortality and provide a valuable summary to policymakers for developing policies and strategies promoting high-quality maternal healthcare.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11101123 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0293197 | PLOS |
BMJ Open
January 2025
Centre for Primary Care and Public Health, Queen Mary University of London Wolfson Institute of Preventive Medicine, London, UK.
Objective: In the UK and worldwide, there are substantial ethnic inequalities in maternal and perinatal care and outcomes. We aim to assess the impact of the unprecedented change in care provision during the COVID-19 pandemic on inequalities in adverse maternity outcomes.
Design: Retrospective cohort study using structured electronic health record data.
BMJ Glob Health
January 2025
Women's and Children's Health, University of Liverpool, Liverpool, UK.
Background: Despite strong evidence-based strategies for prevention and management, global efforts to reduce deaths from postpartum haemorrhage (PPH) have failed, and it remains the leading cause of maternal mortality. We conducted a detailed review of all maternal deaths from 33 facilities in Malawi to identify health system weaknesses leading to deaths from PPH.
Methods: Data were collected regarding every maternal death occurring across all district and central hospitals in Malawi.
BMJ Ment Health
January 2025
Department of Primary Care and Population Health, University College London, London, UK.
Background: There is some evidence that perinatal anxiety (PNA) is associated with lower rates of infant vaccinations and decreased access to preventative infant healthcare, but results across studies have not been conclusive.
Objective: To investigate the relationship between maternal PNA and infant primary care use.
Methods: Cohort study of mother-infant pairs identified between 1998 and 2016 using IQVIA Medical Research Database (IMRD).
Environ Res
January 2025
Department of Laboratory Medicine, Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden; Department of Clinical Pharmacology, Pharmacy and Environmental Medicine, Institute of Public Health, University of Southern Denmark, Odense, Denmark.
Background: Perfluorinated alkyl substances (PFAS) are suggested to impair immune function in children. Previous studies investigating associations between prenatal PFAS exposure and common infections were performed in background-exposed populations whilst studies from high-exposed populations are lacking.
Objectives: To investigate the association between prenatal PFAS exposure from contaminated drinking water and common infections in children aged 6 months to 7 years in Ronneby, Sweden.
Am J Obstet Gynecol MFM
January 2025
School of Medicine, Tufts University; Tufts Medical Center.
Objective: The maternal metabolic environment in early pregnancy can influence fetal growth trajectories. Our objective was to identify interventions initiated in early pregnancy (<20 weeks gestation) in pregnant individuals with risk factors for hyperglycemia and report their impact on primary (neonatal adiposity, small for gestational age, large for gestational age, macrosomia) and secondary outcomes (gestational weight gain, maternal hypertensive disorder, birth injury, NICU admission, preterm delivery, emergency cesarean section).
Data Sources: We searched Cochrane Central database, Medline, Embase, CINAHL databases, and clinicaltrials.
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