Irradiation of CBA mice elicits a pronounced response of intrathymus and bone marrow precursors of T-lymphocytes (PTL) which is manifested by an increase in a relative content of PTL in the thymus and their transfer from bone marrow to thymus. The estimate of the regenerative potency of the thymus most adequately reflects the cellular events leading to regeneration thereof. The differences in the thymus regeneration dynamics between CBA and AKR mice are associated with different radiation response of the intrathymic SC-1-PTL in mice of these strains.
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