AI Article Synopsis

  • Self-monitoring of glucose is crucial for diabetes management, but current methods are often invasive and uncomfortable for users.
  • This study tested a noninvasive glucose monitoring system that uses a wrist-mounted sensor and AI to predict glucose levels from microwave signal variations.
  • Results showed an average predictive accuracy (MARD) of 10.3%, indicating that this new method could potentially rival existing commercial glucose monitoring options, providing a better experience for users.

Article Abstract

Background: Self-monitoring of glucose is important to the successful management of diabetes; however, existing monitoring methods require a degree of invasive measurement which can be unpleasant for users. This study investigates the accuracy of a noninvasive glucose monitoring system that analyses spectral variations in microwave signals.

Methods: An open-label, pilot design study was conducted with four cohorts (N = 5/cohort). In each session, a dial-resonating sensor (DRS) attached to the wrist automatically collected data every 60 seconds, with a novel artificial intelligence (AI) model converting signal resonance output to a glucose prediction. Plasma glucose was measured in venous blood samples every 5 minutes for Cohorts 1 to 3 and every 10 minutes for Cohort 4. Accuracy was evaluated by calculating the mean absolute relative difference (MARD) between the DRS and plasma glucose values.

Results: Accurate plasma glucose predictions were obtained across all four cohorts using a random sampling procedure applied to the full four-cohort data set, with an average MARD of 10.3%. A statistical analysis demonstrates the quality of these predictions, with a surveillance error grid (SEG) plot indicating no data pairs falling into the high-risk zones.

Conclusions: These findings show that MARD values approaching accuracies comparable to current commercial alternatives can be obtained from a multiparticipant pilot study with the application of AI. Microwave biosensors and AI models show promise for improving the accuracy and convenience of glucose monitoring systems for people with diabetes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11571554PMC
http://dx.doi.org/10.1177/19322968241252819DOI Listing

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