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Multi-channel multiplexing metasurfaces have attracted considerable interest with the growing demand for multifunctional integration and enhanced communication capabilities. Dynamic tuning of electromagnetic waves with multiple degrees of freedom is a key approach to improving information processing capabilities. Metasurfaces with chiral meta-atoms and Janus metasurfaces with asymmetric transmission properties introduce new degrees of freedom for multiplexing technologies.
View Article and Find Full Text PDFLipid nanoparticle-mediated intracameral mRNA delivery facilitates gene expression and editing in the anterior chamber of the eye.
J Control Release
January 2025
Department of Pharmaceutical Sciences, College of Pharmacy, Robertson Life Sciences Building, Oregon State University, Portland, OR 97201, USA; Department of Ophthalmology, Casey Eye Institute, Oregon Health & Science University, Portland, OR 97239, USA; Department of Biomedical Engineering, Robertson Life Sciences Building, Oregon Health & Science University, Portland, OR 97201, USA. Electronic address:
Lipid nanoparticles (LNPs) have shown great potential in the field of gene therapy for retinal diseases. To expand on this application, we investigated LNP-mediated mRNA delivery to the anterior chamber of the eye via the intracameral (IC) route of administration. Here, we show that IC injections of LNPs facilitated protein expression and gene editing in the trabecular meshwork (TM).
View Article and Find Full Text PDFonEEGwaveLAD: A fully automated online EEG wavelet-based learning adaptive denoiser for artefacts identification and mitigation.
PLoS One
January 2025
Trinity Centre for Biomedical Engineering, Trinity College Dublin, Dublin, Ireland.
Electroencephalographic signals are obtained by amplifying and recording the brain's spontaneous biological potential using electrodes positioned on the scalp. While proven to help find changes in brain activity with a high temporal resolution, such signals are contaminated by non-stationary and frequent artefacts. A plethora of noise reduction techniques have been developed, achieving remarkable performance.
View Article and Find Full Text PDFArtificial Intelligence and Neuroscience: Transformative Synergies in Brain Research and Clinical Applications.
J Clin Med
January 2025
Department of Neurosurgery, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
The convergence of Artificial Intelligence (AI) and neuroscience is redefining our understanding of the brain, unlocking new possibilities in research, diagnosis, and therapy. This review explores how AI's cutting-edge algorithms-ranging from deep learning to neuromorphic computing-are revolutionizing neuroscience by enabling the analysis of complex neural datasets, from neuroimaging and electrophysiology to genomic profiling. These advancements are transforming the early detection of neurological disorders, enhancing brain-computer interfaces, and driving personalized medicine, paving the way for more precise and adaptive treatments.
View Article and Find Full Text PDFThe Experience of Social Exclusion and the Path to Inclusion from the Perspectives of Immigrant and Refugee Women in the Niagara Region.
Int J Environ Res Public Health
December 2024
Tools of Empowerment for Success (TOES Niagara), Welland, ON L3B 3W7, Canada.
Social inclusion is a common goal for equitable access to resources for living, is important to health and wellbeing, and is supported by most Western or developed nations. Despite this, immigrant and refugee women continue to be excluded from social, cultural, economic, civic, and political participation during and after settlement. Most research exploring the context of social exclusion has reinforced that some groups experience greater exclusion than others in any given population, for example, immigrant women.
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