Background: The aim of this study was to evaluate the efficacy of atmospheric pressure cold plasma jet and plasma activated medium (PAM) on sciatic nerve injury (SNI).
Materials And Methods: Rats were divided into 6 groups (n = 10); group 1 (sham), group 2 (SNI), group 3 (SNI + atmospheric pressure cold plasma jet 5 min), group 4 (SNI + atmospheric pressure cold plasma jet 10 min), group 5 (SNI + PAM 5 min), and group 6 (SNI + PAM 10 min). On days 1, 8, 15, and 22 of the study, atmospheric pressure cold plasma jet was applied to rats in groups 3 and 4, and PAM was applied to rats in groups 5 and 6. A hot plate test was applied to all rats on the same days. On day 28, the experiment was terminated, and sciatic nerve tissues were removed for histopathological evaluation.
Results: According to the 4-week average of the hot plate tests, a significant relationship was found between group 2 and group 4 and group 6 (p < 0.05). When evaluated within each week, significant differences were found between group 2 and group 4 in week 1, between group 2 and group 5 and group 6 in week 2, between group 2 and group 4 in week 3, and between group 2 and group 4 and group 6 in week 4 (p < 0.05). As a result of histopathological analysis, except for the control group, the other groups had similar characteristics in terms of axonal degeneration, periaxonal swelling, and axon density.
Conclusions: As a result of our study, we found that plasma application showed an improvement in the duration of the hot plate test but did not show any improvement histopathologically.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5603/fm.100019 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Mortality Trends in Polymyositis and Dermatomyositis in Mexico: A General Population-Based Study From 2000 to 2019.
J Clin Rheumatol
March 2025
Coordinación de Investigación en Salud, Instituto Mexicano del Seguro Social, Puebla, Mexico.
Introduction: Patients with polymyositis and dermatomyositis (PM/DM) are prone to multiple complications that may lead to increased mortality rates. Data about PM/DM mortality in Mexico are lacking.
Objective: The aim of this study was to assess mortality trends in PM/DM in Mexico across 2 decades (2000-2019), overall, by sex, age group, and geographic region.
Supplementation of a Basal Goat Diet With Incremental Doses of Canola Essential Oil Modulates In Vitro Rumen Fermentation and Microbial Diversity.
Vet Med Sci
March 2025
Department of Animal Science, Faculty of Natural and Agricultural Science, North-West University, Mmabatho, South Africa.
Background: Canola essential oil (CEO) contains linoleic and oleic fatty acids that can inhibit the growth of pathogenic micro-organisms and alter microbial digestion to increase ruminal fermentation and nutrient utilisation.
Objectives: The study evaluated the effect of supplementing a basal goat diet with incremental doses of CEO on chemical constituents and in vitro ruminal fermentation parameters and microbial diversity.
Methods: Experimental treatments were a basal goat diet containing 0.
Examining Potential Mediators of the Relationship Between Developmental Language Disorder and Executive Function Performance in Preschoolers.
J Speech Lang Hear Res
March 2025
Department of Speech, Language, and Hearing Sciences, The University of Arizona, Tucson.
Purpose: The goal of this study was to examine potential mediators of the relationship between developmental language disorder (DLD) status and executive function performance.
Method: Participants included preschoolers, of whom 80 met the diagnostic criteria for DLD and 103 were categorized as having typical language abilities. Participants' nonverbal IQ and receptive vocabulary were assessed via standardized tests, and their executive function was tested using the Dimensional Change Card Sort.
Noninfectious Uveitis in Pediatric Rheumatology: Long-term Follow-up at Tertiary Centers.
J Clin Rheumatol
March 2025
From the Department of Pediatric Rheumatology, Istanbul University-Cerrahpaşa, Cerrahpaşa Medical School.
Objectives: Our study aimed to identify potential predictors for additional systemic involvement in patients with noninfectious uveitis, specifically focusing on their demographic, etiological, clinical, and laboratory data features from the pediatric rheumatology perspective.
Methods: Patients with noninfectious uveitis before the age of 18 years and followed up for at least 3 months in 2 tertiary centers of pediatric rheumatology and ophthalmology departments were included in the study. Demographics, etiology, clinical features, laboratory data, and treatments administered were evaluated and compared based on the etiology (idiopathic and systemic disease-related uveitis [SD-U]) and the use of biologic disease-modifying antirheumatic drugs.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!