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Patterns in affect and personality states across the menstrual cycle.
J Pers Soc Psychol
January 2025
Melbourne School of Psychological Sciences, University of Melbourne.
Affective, behavioral, and cognitive (i.e., personality) states fluctuate across situations and context, yet the biological mechanisms regulating them remain unclear.
View Article and Find Full Text PDFEffect of Caloric Restriction and Aerobic Exercise on Premenstrual Syndrome, Anthropometric, and Hormonal Parameters in Obese Females: A Randomized Controlled Trial.
Physiother Res Int
January 2025
Department of Physical Therapy for Women's Health, Cairo University, Giza, Egypt.
Background And Purpose: Premenstrual syndrome (PMS) affects physical, psychological, and behavioral symptoms in women. Obesity may worsen PMS, but the impact of caloric restriction and aerobic exercise on PMS in obese women is unclear. This study examines their effects on PMS, anthropometric, and hormonal parameters in obese females.
View Article and Find Full Text PDFAllopregnanolone and mood in the peripartum: a longitudinal assessment in healthy women.
Front Behav Neurosci
November 2024
Clinical Psychology and Psychotherapy, University of Zurich, Zürich, Switzerland.
Background: Allopregnanolone (ALLO), a neuroactive steroid hormone derived from progesterone, can modulate mood via the GABA-A receptor. Peripartum mood can be influenced by psychosocial factors, previous mental illness, and hormonal changes. Studies suggest a U-shaped effect of ALLO on mood, with some women being more sensitive to hormonal changes than others.
View Article and Find Full Text PDFNeuroactive steroid levels are elevated in the follicular phase and predict premenstrual depression and anxiety symptom severity in women with menstrually related mood disorder.
Arch Womens Ment Health
November 2024
Neuroendocrine Unit, Massachusetts General Hospital, 50 Staniford St., Suite 750B, Boston, MA, 02114, USA.
Article Synopsis
- Menstrually related mood disorder (MRMD) is characterized by severe emotional symptoms occurring in the late luteal phase of the menstrual cycle, which may be linked to low levels of the neuroactive steroid allopregnanolone due to lesser conversion from progesterone.
- In a study with nine women with MRMD and fourteen healthy controls, MRMD was diagnosed using the DSM-5 criteria, and symptoms of depression and anxiety, as well as plasma neuroactive steroid levels, were assessed at different phases of the menstrual cycle.
- Results showed that while women with MRMD had higher allopregnanolone levels in the mid-follicular phase, they experienced greater depression severity only in the late luteal phase, suggesting a
HY7801 Improves Premenstrual Syndrome Symptoms by Regulating Sex Hormones and Inflammatory Cytokines in a Mouse Model of Metoclopramide-Induced Hyperprolactinemia.
Nutrients
November 2024
R&BD Center, hy Co., Ltd., 22, Giheungdanji-ro 24 Beon-gil, Giheung-gu, Yongin-si 17086, Republic of Korea.
Article Synopsis
- Premenstrual syndrome (PMS) causes significant physical and psychological symptoms during the luteal phase of the menstrual cycle and can greatly affect quality of life.
- This study examined the effects of HY7801 on PMS by conducting lab tests and experiments on mice, finding that it significantly inhibits harmful hormone and cytokine secretion.
- Results suggest that HY7801 can help alleviate PMS symptoms by balancing hormones and reducing inflammation in the body.
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