This analysis of 116 isavuconazole therapy courses shows that hepatic test disturbances (HTDs) were relatively frequent (29% of cases) but rarely led to treatment interruption (5%). Importantly, patients with baseline HTDs, including those attributed to a first-line triazole, did not exhibit a higher risk of subsequent HTD under isavuconazole therapy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097116PMC
http://dx.doi.org/10.1093/ofid/ofae223DOI Listing

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