We investigate analytically the distribution tails of the area A and perimeter L of a convex hull for different types of planar random walks. For N noninteracting Brownian motions of duration T we find that the large-L and -A tails behave as P(L)∼e^{-b_{N}L^{2}/DT} and P(A)∼e^{-c_{N}A/DT}, while the small-L and -A tails behave as P(L)∼e^{-d_{N}DT/L^{2}} and P(A)∼e^{-e_{N}DT/A}, where D is the diffusion coefficient. We calculated all of the coefficients (b_{N},c_{N},d_{N},e_{N}) exactly. Strikingly, we find that b_{N} and c_{N} are independent of N for N≥3 and N≥4, respectively. We find that the large-L (A) tails are dominated by a single, most probable realization that attains the desired L (A). The left tails are dominated by the survival probability of the particles inside a circle of appropriate size. For active particles and at long times, we find that large-L and -A tails are given by P(L)∼e^{-TΨ_{N}^{per}(L/T)} and P(A)∼e^{-TΨ_{N}^{area}(sqrt[A]/T)}, respectively. We calculate the rate functions Ψ_{N} exactly and find that they exhibit multiple singularities. We interpret these as DPTs of first order. We extended several of these results to dimensions d>2. Our analytic predictions display excellent agreement with existing results that were obtained from extensive numerical simulations.
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http://dx.doi.org/10.1103/PhysRevE.109.044120 | DOI Listing |
Nat Commun
December 2024
Beijing Life Science Academy, Beijing, China.
Nipah virus (NiV) is a non-segmented, negative-strand (NNS) RNA virus, belonging to Paramyxoviridae. The RNA polymerase complex, composed of large (L) protein and tetrameric phosphoprotein (P), is responsible for genome transcription and replication by catalyzing NTP polymerization, mRNA capping and cap methylation. Here, we determine the cryo-electron microscopy (cryo-EM) structure of fully bioactive NiV L-P polymerase complex at a resolution of 3.
View Article and Find Full Text PDFPhys Rev E
April 2024
Department of Environmental Physics, Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev, Sede Boqer Campus, 8499000, Israel.
We investigate analytically the distribution tails of the area A and perimeter L of a convex hull for different types of planar random walks. For N noninteracting Brownian motions of duration T we find that the large-L and -A tails behave as P(L)∼e^{-b_{N}L^{2}/DT} and P(A)∼e^{-c_{N}A/DT}, while the small-L and -A tails behave as P(L)∼e^{-d_{N}DT/L^{2}} and P(A)∼e^{-e_{N}DT/A}, where D is the diffusion coefficient. We calculated all of the coefficients (b_{N},c_{N},d_{N},e_{N}) exactly.
View Article and Find Full Text PDFJ Gen Virol
April 2024
Icahn School of Medicine at Mount Sinai, New York, NY, USA.
J Gen Virol
December 2023
School of Life Sciences and Human Phenome Institute, Fudan University, Shanghai 201052, PR China.
J Gen Virol
December 2023
Institute for Sustainable Plant Protection, National Research Council of Italy (IPSP-CNR), 10135 Torino, Italy.
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