Phased array ultrasonic testing (PAUT) requires highly trained and qualified personnel to interpret and analyze images. It takes a solid understanding of wave propagation physics to comprehend the generated images. As such, the inspector's judgment and level of experience have a significant impact on the analysis's outcome. In addition, the procedure is prone to error and laborious. AI had shown to be effective in computer vision in a variety of classification and detection tasks. Regarding PAUT, studies have also demonstrated that machine learning may be able to identify defects with a level of accuracy that is on par or even superior to that of trained and qualified inspectors. Nonetheless, the use of computer vision in PAUT remains very limited. The primary cause of this is the challenge accessing large databases of labelled inspections. In fact, a considerable amount of training data is required for machine learning. While it is easy to access sizeable, labelled databases of MRI scans or photographs for instance, that is not the case in PAUT because inspection results are usually confidential. In this project, a large database was generated using mock-ups commonly used to train and evaluate inspectors. The different defects contained in these mock-ups were used to train a machine learning model. The data was acquired with several different probes centered at different frequencies. Each acquisition was performed using Full Matrix Capture (FMC). The post-processing of the data contained in the FMC allows to compute any sectoral scan from its focal laws. As a result, a comprehensive database composed of hundreds of thousands of sectoral scans was generated from these few FMC acquisitions. The completeness of this database facilitated robust training of a defect detection model for PAUT sectoral scans. The evaluation of the model demonstrated its ability to generalize even to defect types it had never been trained on. Furthermore, the detection performance remained consistent even in high noise conditions where the Contrast-to-Noise Ratio (CNR) was very low.
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http://dx.doi.org/10.1016/j.ultras.2024.107316 | DOI Listing |
Medicine (Baltimore)
January 2025
Department of Otolaryngology, Hangzhou Red Cross Hospital (Zhejiang Hospital of Integrated Traditional Chinese and Western Medicine), Hangzhou, Zhejiang, China.
T-helper 17 (Th17) cells significantly influence the onset and advancement of malignancies. This study endeavor focused on delineating molecular classifications and developing a prognostic signature grounded in Th17 cell differentiation-related genes (TCDRGs) using machine learning algorithms in head and neck squamous cell carcinoma (HNSCC). A consensus clustering approach was applied to The Cancer Genome Atlas-HNSCC cohort based on TCDRGs, followed by an examination of differential gene expression using the limma package.
View Article and Find Full Text PDFAnal Chem
January 2025
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350117, China.
Multiple myeloma is a hematologic malignancy characterized by the proliferation of abnormal plasma cells in the bone marrow. Despite therapeutic advancements, there remains a critical need for reliable, noninvasive methods to monitor multiple myeloma. Circulating plasma cells (CPCs) in peripheral blood are robust and independent prognostic markers, but their detection is challenging due to their low abundance.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Division of Clinical Pathology, Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Background: Sepsis, a critical global health challenge, accounted for approximately 20% of worldwide deaths in 2017. Although the Sequential Organ Failure Assessment (SOFA) score standardizes the diagnosis of organ dysfunction, early sepsis detection remains challenging due to its insidious symptoms. Current diagnostic methods, including clinical assessments and laboratory tests, frequently lack the speed and specificity needed for timely intervention, particularly in vulnerable populations such as older adults, intensive care unit (ICU) patients, and those with compromised immune systems.
View Article and Find Full Text PDFJCO Clin Cancer Inform
January 2025
Machine Learning Department, H. Lee Moffit Cancer Center and Research Institute, Tampa, FL.
Purpose: Adaptive radiotherapy accounts for interfractional anatomic changes. We hypothesize that changes in the gross tumor volumes identified during daily scans could be analyzed using delta-radiomics to predict disease progression events. We evaluated whether an auxiliary data set could improve prediction performance.
View Article and Find Full Text PDFJ Clin Oncol
January 2025
INSERM, IMRBU955, Univ Paris Est Créteil, Créteil, France.
Purpose: Establishing an accurate prognosis remains challenging in older patients with cancer because of the population's heterogeneity and the current predictive models' reduced ability to capture the complex interactions between oncologic and geriatric predictors. We aim to develop and externally validate a new predictive score (the Geriatric Cancer Scoring System [GCSS]) to refine individualized prognosis for older patients with cancer during the first year after a geriatric assessment (GA).
Materials And Methods: Data were collected from two French prospective multicenter cohorts of patients with cancer 70 years and older, referred for GA: ELCAPA (training set January 2007-March 2016) and ONCODAGE (validation set August 2008-March 2010).
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