Secofumitremorgins C and D, a pair of atropisomers from saltern-derived fungus GXIMD00544.

A pair of atropisomers secofumitremorgins C () and D (), together with fifteen known alkaloids (), were isolated from a saltern-derived fungus GXIMD00544. The structures of atropisomers and were elucidated by the detailed spectroscopic data, chemical reaction and quantum chemical calculations. Compounds and displayed antifungal spore germination effects against plant pathogenic fungus associated with sugarcane sp. with inhibitory rates of 53% and 77% at the concentration of 100 µM, repectively. Atropisomers also exhibited antifouling potential against larval settlement with an inhibitory rate of 96% at the concentration of 100 µM.