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Visible-light-induced synthesis of heteroaryl -glycosides decarboxylative C-H glycosylation. | LitMetric

Visible-light-induced synthesis of heteroaryl -glycosides decarboxylative C-H glycosylation.

Chem Commun (Camb)

Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, Department of Medicinal Chemistry, West China School of Pharmacy, Sichuan University, No. 17 Southern Renmin Road, Chengdu, Sichuan 610041, People's Republic of China.

Published: May 2024

A photoredox promoted decarboxylative C-H glycosylation has been developed for the synthesis of heteroaryl -glycosides. This methodology is characterized by its exceedingly simple reaction system, high diastereoselectivity and good functional group tolerance. Moreover, this innovative approach circumvents the need for high temperatures, transition metals, and photocatalysts, providing an environmentally friendly, straightforward, and efficient protocol.

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Source
http://dx.doi.org/10.1039/d4cc01328jDOI Listing

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