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Building a Bridge Between the Mechanism of EBV Reactivation and the Treatment of EBV-Associated Cancers.
J Med Virol
February 2025
Hunan Cancer Hospital and the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, China.
Epstein-Barr virus (EBV) infection is closely associated with the development of various tumors such as lymphomas and epithelial cancers. EBV has a discrete life cycle with latency and lytic phases. In recent years, significant progress has been made in the understanding of the mechanism underlying the transition of EBV from latency to lytic replication.
View Article and Find Full Text PDFA Challenging Case of IgG4-Related Kidney Disease Accompanied With Positive Serologic Tests of Lupus Erythematosus.
Nephrology (Carlton)
January 2025
Division of Nephrology, Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
The case report presents a male patient in his mid-60s with a history of hypertension, benign prostatic hyperplasia and chronic kidney disease (CKD). He presented with gradually increasing serum creatinine levels and hyperglobulinemia, leading to suspicion of multiple myeloma. However, subsequent testing revealed features consistent with systemic lupus erythematosus (SLE) and IgG4-related kidney disease (IgG4-RKD).
View Article and Find Full Text PDFThe FEBS 60th anniversary writing contest-blueprints for the scientific society of tomorrow.
FEBS Lett
December 2024
FEBS Letters Editorial Office, Cambridge, UK.
The Federation of European Biochemical Societies (FEBS) celebrated its 60th anniversary in 2024, and FEBS Letters marked the occasion with a writing contest on the future of scientific societies. This editorial introduces the winning article by Yussuf Ali and presents an overview of the predominant themes that emerged during the contest, which included AI, interdisciplinarity, diversity and sustainability.
View Article and Find Full Text PDFNear-atomic cryo-EM structure of the light-harvesting complex LH2 from the sulfur purple bacterium Ectothiorhodospira haloalkaliphila.
Structure
December 2024
Bach Institute of Biochemistry, Research Center of Biotechnology Russian Academy of Sciences, Leninsky pr-t, 33, bld. 2, Moscow 119071, Russia. Electronic address:
Bacteria with the simplest system for solar energy absorption and conversion use various types of light-harvesting complexes for these purposes. Light-harvesting complex 2 (LH2), an important component of the bacterial photosynthetic apparatus, has been structurally well characterized among purple non-sulfur bacteria. In contrast, so far only one high-resolution LH2 structure from sulfur bacteria is known.
View Article and Find Full Text PDFMeasurement of the electric potential and the magnetic field in the shifted analysing plane of the KATRIN experiment.
Eur Phys J C Part Fields
December 2024
The projected sensitivity of the effective electron neutrino-mass measurement with the KATRIN experiment is below 0.3 eV (90 % CL) after 5 years of data acquisition. The sensitivity is affected by the increased rate of the background electrons from KATRIN's main spectrometer.
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