We report a patient with behavioral variant frontotemporal dementia who developed agraphia, irritability, perseverative and stereotyped behavior, and dietary changes. MRI revealed bilateral frontal convexity atrophy. Neuropsychological examination showed fluent aphasia with perseverative allographic agraphia, mild semantic impairment, and dysexecutive syndrome. Allographic agraphia featured unidirectional conversion from (cursive form of Japanese phonograms) and (Japanese morphograms) to (square form of Japanese phonograms), as opposed to mutual (bidirectional) conversion between and in parieto-occipital gyri lesions. Furthermore, all letters of the word were converted and this whole-word conversion may be characteristic of perseverative behavior in frontotemporal dementia.
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http://dx.doi.org/10.1080/13554794.2024.2353936 | DOI Listing |
Neurocase
February 2024
Department of Neurology, Takuma Neurology Clinic, Tokyo, Japan.
We report a patient with behavioral variant frontotemporal dementia who developed agraphia, irritability, perseverative and stereotyped behavior, and dietary changes. MRI revealed bilateral frontal convexity atrophy. Neuropsychological examination showed fluent aphasia with perseverative allographic agraphia, mild semantic impairment, and dysexecutive syndrome.
View Article and Find Full Text PDFFront Hum Neurosci
November 2022
Department of Speech, Language, and Hearing Sciences, The University of Arizona, Tucson, AZ, United States.
Language performance requires support from central cognitive/linguistic abilities as well as the more peripheral sensorimotor skills to plan and implement spoken and written communication. Both output modalities are vulnerable to impairment following damage to the language-dominant hemisphere, but much of the research to date has focused exclusively on spoken language. In this study we aimed to examine an integrated model of language processing that includes the common cognitive processes that support spoken and written language, as well as modality-specific skills.
View Article and Find Full Text PDFCortex
November 2021
Department of Neuroscience & Padova Neuroscience Center, University of Padova, Padova, Italy; IRCCS San Camillo Hospital, Venice, Italy. Electronic address:
"Macrographia", a relatively rare symptom generally following cerebellar diseases, consists of an abnormally large handwriting. The case reported in the present investigation shows several outstanding features. First, it is of the progressive variety, letters increase in size as one goes through the word towards the lower-right portion of space.
View Article and Find Full Text PDFIntern Med
July 2018
Departments of Rehabilitation, National Hospital Organization Higashi-ohmi General Medical Center, Japan.
Japanese people born before World War II learned Japanese kana (Japanese syllabograms) writing in a style that is not currently used. These individuals had to learn the current style of kana orthography after the war. An 85-year-old man was taken to our hospital by his family who were surprised by his diary.
View Article and Find Full Text PDFNeuropsychol Rehabil
October 2019
Department of Speech, Language, and Hearing Sciences, The University of Arizona, Tucson , AZ , USA.
Maximal recovery from acquired language impairment may require progression from one behavioural treatment protocol to the next in order to build upon residual and relearned cognitive-linguistic and sensory-motor processes. We present a five-stage treatment sequence that was initiated at one year post stroke in a woman with acquired impairments of spoken and written language. As is typical of individuals with left perisylvian damage, she demonstrated marked impairment of phonological retrieval and sublexical phonology, but she also faced additional challenges due to impaired letter shape knowledge and visual attention.
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