Drug-resistant shigellosis is increasing, particularly among men who have sex with men (MSM). During July-October 2022, an extended-spectrum beta-lactamase producing Shigella sonnei cluster of 9 patients was identified in Chicago, of whom 8 were MSM and 6 were festival attendees. The cluster also included 4 domestic travelers to Chicago. Sexual health care for MSM should include shigellosis diagnosis and prevention.
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http://dx.doi.org/10.1093/infdis/jiae235 | DOI Listing |
Metabolites
December 2024
Department of Clinical Laboratory, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, China.
Background: Bloodstream infections (BSIs) pose a great challenge to treating patients, especially those with underlying diseases, such as immunodeficiency diseases. Early diagnosis helps to direct precise empirical antibiotic administration and proper clinical management. This study carried out a serum metabolomic analysis using blood specimens sampled from patients with a suspected infection whose routine culture results were later demonstrated to be positive.
View Article and Find Full Text PDFBMC Public Health
December 2024
Center for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.
Background: Wastewater-based epidemiology (WBE) is already being adopted for the surveillance of health conditions of communities and shows great potential for the monitoring of infectious pathogens of public health importance. There is however paucity of robust data to support extensive WBE in Nigeria. This study evaluated the prevalence of clinically relevant infectious pathogens and provided antimicrobial resistance profiles of bacteria pathogens in wastewater canals in Lagos State at a single point in time.
View Article and Find Full Text PDFJ Infect Chemother
December 2024
Department of Pediatrics, Dokkyo Medical University, Tochigi, Japan.
The incidence of urinary tract infection (UTI) caused by extensive beta-lactamase-producing Escherichia coli (ESBL-EC) is increasing, including in children. However, the available oral antibiotic treatment options for ESBL-EC are limited. Herein, we report the cases of two children diagnosed with UTI caused by ESBL-EC (ESBL-UTI) who were switched from empirical intravenous antibiotics in UTI to amoxicillin-clavulanic acid (AMPC/CVA) (14:1) after the causative organism was found to be ESBL-EC.
View Article and Find Full Text PDFFront Microbiol
December 2024
College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Introduction: The development of extended-spectrum-beta-lactamase (ESBLs) () has become a global threat to public health. An alternative strategy to alleviate this is identifying potential natural compounds to restore antibiotic activity against ESBLs . This study aimed to find a possible compound to restore ESBLs sensitivity to ceftiofur.
View Article and Find Full Text PDFVet Microbiol
December 2024
One Health Brazilian Resistance Project (OneBR), Brazil; Department of Microbiology, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, Brazil; Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil; Department of Pathology, School of Veterinary Medicine and Animal Science, University of São Paulo, São Paulo, Brazil. Electronic address:
Extended-spectrum β-lactamase (ESBL)-producing Escherichia coli poses a significant threat to public health due to its ability to confer resistance to broad-spectrum antimicrobials, especially third-generation cephalosporins. Herein, we report gut colonization by international clones of CTX-M-8-producing E. coli in scorpion mud turtles (Kinosternon scorpioides) from a captive breeding program in the Brazilian Amazon.
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