Alopecia areata (AA) is an autoimmune-related disorder characterized by non-scarring hair loss in children. We report the case of a child who had AA after the fifth dose of rabies vaccine and summarized various potential mechanisms of vaccination induced AA. This case indicates that rabies vaccine might be a predisposition of AA by causing immune dysregulation.
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http://dx.doi.org/10.7774/cevr.2024.13.2.171 | DOI Listing |
Int J Mol Sci
December 2024
Epi Biotech Co., Ltd., Incheon 21983, Republic of Korea.
We previously demonstrated that C-X-C Motif Chemokine Ligand 12 (CXCL12) is primarily secreted by dermal fibroblasts in response to androgens and induces hair miniaturization in the mouse androgenic alopecia (AGA) model. However, the direct effects of androgen-induced CXCL12 on dermal papilla cells (DPCs) and dermal sheath cup cells (DSCs) have not been demonstrated. First, we compared single-cell RNA sequencing data between mouse and human skin, and the results show that CXCL12 is highly co-expressed with the androgen receptor (AR) in the DPCs and DSCs of only human hair.
View Article and Find Full Text PDFJAAD Int
February 2025
Department of Dermatology, University of California, San Francisco, California.
Lasers Surg Med
January 2025
Dermatology, Venereology and Andrology Department, Faculty of Medicine, Tanta University, Tanta, Egypt.
Background: Alopecia areata (AA) is a chronic inflammatory disease that affects the hair follicles and sometimes the nails. It usually presents as a single or multiple patches of hair loss on the scalp, but any hair-bearing skin can be involved. AA treatment depends on the severity and extent of the disease.
View Article and Find Full Text PDFActa Derm Venereol
January 2025
Department of Preventive Medicine, Korea University College of Medicine, Seoul, Korea.
Data on pregnancy outcomes in patients with alopecia areata (AA) are limited. The aim of this study is to determine the association between maternal AA and risk of adverse birth outcomes in children. A retrospective cohort study was conducted on 45,328 children born to mothers with AA and 4,703,253 controls born to mothers without AA using the Korean National Health Insurance Claims database from 2002 to 2016.
View Article and Find Full Text PDFBMC Med Inform Decis Mak
January 2025
Department of Digital Systems, University of Piraeus, Piraeus, Greece.
Vitiligo, alopecia areata, atopic, and stasis dermatitis are common skin conditions that pose diagnostic and assessment challenges. Skin image analysis is a promising noninvasive approach for objective and automated detection as well as quantitative assessment of skin diseases. This review provides a systematic literature search regarding the analysis of computer vision techniques applied to these benign skin conditions, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.
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