AI Article Synopsis
- This study investigates how effective global longitudinal strain (GLS) is at detecting heart issues in patients experiencing chest pain during treadmill contrast-enhanced stress echocardiography.
- The research involved analyzing data from 33 patients who underwent further testing for coronary artery issues, finding that those with significant blockages had notably lower GLS measurements.
- The findings suggest that GLS can be a helpful diagnostic tool, particularly with a threshold of -20% in stress measurements indicating a reasonable accuracy for ruling out myocardial ischemia.
Article Abstract
Introduction: The aim of this study is to analyze the diagnostic value of global longitudinal strain (GLS) in detecting inducible myocardial ischemia in patients with chest pain undergoing treadmill contrast-enhanced stress echocardiography (SE).
Methods: We retrospectively enrolled all patients who underwent invasive coronary angiography after treadmill contrast-enhanced SE. Rest and peak-stress myocardial GLS, segmental LS, and LS of 4-chamber (CH), 2-CH, and 3-CH views were reported. Luminal stenosis of more than 70% or fractional flow reserve (FFR) of < 0.8 was considered significant.
Results: In total 33 patients were included in the final analysis, among whom sixteen patients (48.4%) had significant coronary artery stenosis. Averaged GLS, 3-CH, and 4-CH LS were significantly lower in patients with critical coronary artery stenosis compared to those without significant stenosis (-17.1 ± 7.1 vs. -24.2 ± 7.2, p = 0.041), (-18.2 ± 8.9 vs. -24.6 ± 8.2, p = 0.045) and (-14.8 ± 6.2 vs. -22.8 ± 7.8, p = 0.009), respectively. Receiver operating characteristic (ROC) analysis of ischemic and non-ischemic segments demonstrated that a cut-off value of -20% of stress LS had 71% sensitivity and 60% specificity for ruling out inducible myocardial ischemia (Area under the curve was AUC = 0.72, P < 0.0001).
Conclusion: Myocardial LS measured with treadmill contrast-enhanced stress echocardiography demonstrates potential value in identifying patients with inducible myocardial ischemia.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11097493 | PMC |
| http://dx.doi.org/10.1186/s12872-024-03926-8 | DOI Listing |
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Article Synopsis
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- The research involved analyzing data from 33 patients who underwent further testing for coronary artery issues, finding that those with significant blockages had notably lower GLS measurements.
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