AI Article Synopsis
- The FDA Modernization Act 2.0, passed in 2022, encourages the use of new methods to evaluate how drug candidates affect humans.
- Researchers are focusing on microphysiological systems, which use human-derived induced pluripotent stem cells, to predict drug effects more accurately.
- Progress includes addressing challenges in this field and leveraging artificial intelligence tools for better data analysis and predictions.
Article Abstract
The passage of the FDA Modernization Act 2.0 in 2022 has provided additional impetus to develop new approach methods for predicting the effects of drug candidates in humans from models such as microphysiological systems based on human-derived induced pluripotent stem cells. Here, we highlight progress in the field and strategies to address various challenges, including the application of artificial intelligence tools.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11482555 | PMC |
| http://dx.doi.org/10.1038/d41573-024-00081-9 | DOI Listing |
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