Background: In addition to other stroke-related deficits, the risk of seizures may impact driving ability after stroke.
Methods: We analysed data from a multicentre international cohort, including 4452 adults with acute ischaemic stroke and no prior seizures. We calculated the Chance of Occurrence of Seizure in the next Year (COSY) according to the SeLECT prognostic model. We considered COSY<20% safe for private and <2% for professional driving, aligning with commonly used cut-offs.
Results: Seizure risks in the next year were mainly influenced by the baseline risk-stratified according to the SeLECT score and, to a lesser extent, by the poststroke seizure-free interval (SFI). Those without acute symptomatic seizures (SeLECT 0-6 points) had low COSY (0.7%-11%) immediately after stroke, not requiring an SFI. In stroke survivors with acute symptomatic seizures (SeLECT 3-13 points), COSY after a 3-month SFI ranged from 2% to 92%, showing substantial interindividual variability. Stroke survivors with acute symptomatic status epilepticus (SeLECT 7-13 points) had the highest risk (14%-92%).
Conclusions: Personalised prognostic models, such as SeLECT, may offer better guidance for poststroke driving decisions than generic SFIs. Our findings provide practical tools, including a smartphone-based or web-based application, to assess seizure risks and determine appropriate SFIs for safe driving.
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http://dx.doi.org/10.1136/jnnp-2024-333505 | DOI Listing |
Resuscitation
January 2025
Department of Surgery, Division of Congenital Cardiac Surgery, University of Washington, Seattle Children's Hospital, Seattle, WA.
Background: While several studies have reported on outcomes of extracorporeal membrane oxygenation (ECMO) in patients with single ventricle physiology, few studies have described outcomes of extracorporeal cardiopulmonary resuscitation (ECPR) in this unique population. The objective of this study was to determine survival and risk factors for mortality after ECPR in single ventricle patients prior to superior cavopulmonary anastomosis, using a large sample from the Extracorporeal Life Support Organization (ELSO) Registry.
Methods: We included single ventricle patients who underwent ECPR for in-hospital cardiac arrest (IHCA) between January 2012 and December 2021.
Surg Neurol Int
December 2024
Department of Medicine, University of Hawai'i at Mānoa, John A. Burns School of Medicine, Honolulu, Hawaii, USA.
Background: One avenue to improve outcomes among brain tumor patients involves the mitigation of healthcare disparities. Investigating clinical differences among brain tumors across socioeconomic and demographic strata, such can aid in healthcare disparity identification and, by extension, outcome improvement.
Methods: Utilizing a racially diverse population from Hawaii, 323 cases of brain tumors (meningiomas, gliomas, schwannomas, pituitary adenomas, and metastases) were matched by age, sex, and race to 651 controls to investigate the associations between tumor type and various demographic, socioeconomic, and medical comorbidities.
Indian J Pediatr
January 2025
Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.
Objectives: To determine the prevalence of psychiatric morbidities in survivors of pediatric acute lymphoblastic leukemia (ALL) and to identify any risk factors.
Methods: Survivors of ALL, who had completed their treatment, atleast two or more years ago and now were 6-18 y old were enrolled on the study. The Mini International Neuropsychiatric Interview (M.
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