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Extrication following a motor vehicle collision: a consensus statement on behalf of The Faculty of Pre-hospital Care, Royal College of Surgeons of Edinburgh.
Scand J Trauma Resusc Emerg Med
January 2025
Faculty of Pre-Hospital Care, Royal College of Surgeons Edinburgh, Edinburgh, UK.
Background: Road traffic injury is the leading cause of death among young people globally, with motor vehicle collisions often resulting in severe injuries and entrapment. Traditional extrication techniques focus on limiting movement to prevent spinal cord injuries, but recent findings from the EXIT project challenge this approach. This paper presents updated recommendations from the Faculty of Pre-Hospital Care (FPHC) that reflect the latest evidence on extrication practices.
View Article and Find Full Text PDFNon-healing ulcers are chronic lesions, often found on the lower extremities, persisting for over three months despite adequate care. They are associated with systemic diseases or local disorders and significantly impact the quality of life, often resisting conventional treatments, which can be costly and pose side effects. Ta'liq al-Alaq (leech therapy), a regimen in Ilaj-Bit-Tadbeer of Unani medicine, offers an alternative based on the principle of Istifrāgh (expulsion of morbid humours).
View Article and Find Full Text PDFImmunomodulatory effects of medicinal leech saliva extract on in vitro activated macrophages.
Immunol Res
December 2024
Department of Molecular Biology and Genetics, Faculty of Engineering and Natural Sciences, Biruni University, Istanbul, 34010, Turkey.
Leech therapy has been utilized in modern and traditional medicine. Leech saliva contains versatile peptides and molecules that can exert anti-microbial, anti-inflammatory, anti-coagulant, and analgesic activities on the patients. The active components and molecular mechanism of action of these components should be deciphered properly in order to generate biotechnological drug candidates by recombinant production of the leech saliva peptides.
View Article and Find Full Text PDFHirudotherapy Efficacy and Complications in the Management of Microsurgical Breast Reconstruction: A Systematic Review.
World J Plast Surg
January 2024
Division of Plastic and Reconstructive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Background: We aimed to assess the effect of hirudotherapy on flap congestion and thrombosis in adult female patients who underwent microvascular breast reconstruction.
Methods: A systematic review of PubMed, Web of Science, and Cochrane was completed. A qualitative synthesis of all included studies was then performed.
Gut microbiota participates and remodels host metabolism: From treating patients to treating their gut flora.
World J Gastroenterol
December 2024
Department of Clinical Laboratory, The Second Affiliated Hospital of Dalian Medical University, Dalian 116023, Liaoning Province, China.
In this editorial, we comment on Liu s article published in the recent issue of the . Biochemically and pathologically, Liu proved that the urate-lowering activity of leech total protein (LTP) was mainly attributed to the rectification of gut microbiota. Specifically, we noticed the change in and after LTP administration.
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