Purpose: Intimate care products may contain substances associated with increased risk of hormone-related cancers. The relationship between genital talc use and ovarian cancer, in particular, has been well studied, but concerns about recall bias and exposure misclassification have precluded conclusions. We examined the association between intimate care products and female hormone-related cancers, accounting for potential biases, using data from a US-based cohort study.
Methods: The Sister Study enrolled 50,884 women who had a sister with breast cancer. Data on genital talc use and douching were collected at enrollment (2003-2009) and follow-up (2017-2019). We used Cox proportional hazards models to estimate hazard ratios (HRs) for associations between intimate care product use and breast, ovarian, and uterine cancers. To account for potential exposure misclassification and recall bias, we conducted quantitative bias analyses under various exposure reassignment assumptions.
Results: Across considered scenarios, 41%-64% of participants douched and 35%-56% used genital talc. In models adjusted for exposure misclassification, genital talc use was positively associated with ovarian cancer (HR range, 1.17-3.34) Frequent douching and douching during young adulthood were positively associated with ovarian cancer, but neither douching nor talc was associated with breast or uterine cancer. Differential reporting of talc use by cases and noncases likely produces positive biases, but correcting for error still resulted in HRs above 1.0. For example, HR, 1.40 (95% CI, 1.04 to 1.89) when 25% of exposed cases and 10% of unexposed noncases had talc status reassigned.
Conclusion: Although results show how differential recall would upwardly bias estimates, corrected results support a positive association between use of intimate care products, including genital talc, and ovarian cancer.
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http://dx.doi.org/10.1200/JCO.23.02037 | DOI Listing |
Womens Health (Lond)
December 2024
School of Nursing, University of Michigan, Ann Arbor, MI, USA.
Background: Gender-based violence (GBV) is a global public health problem. While research exists on GBV and associated help-seeking behaviors among university students, few studies have assessed the prevalence of GBV, including experiences and barriers to help-seeking, within sub-Saharan African university settings.
Objectives: The objective of this study was to examine the prevalence of GBV victimization among university students in six sub-Saharan African countries and describe experiences of formal and informal help-seeking among students who self-identified as victims of GBV since attending university.
Acad Pediatr
December 2024
University of Maryland School of Medicine, 520 W. Lombard St, Baltimore MD 21201. Electronic address:
Objective: This study introduces the SEEK Teen Questionnaire, expanding the Safe Environment for Every Kid (SEEK) approach to include adolescent perspectives alongside caregiver responses for dual psychosocial screening. The objective of this study aims to triangulate adolescent responses with those of their caregivers to demonstrate the benefits of dual psychosocial screening.
Methods: The SEEK Teen Questionnaire was developed by integrating input from primary care and adolescent medicine professionals, national experts, and adolescent stakeholders.
Violence Against Women
December 2024
Hubert Department of Global Health, Emory University, Atlanta, GA, USA.
This study assessed the relationships between emotional intimate partner violence (IPV) before, during, and after pregnancy and postpartum contraceptive use. We used 2016-2021 Pregnancy Risk Assessment Monitoring System data from seven sites ( = 30,125). We used multivariable logistic regression to assess indicators of emotional IPV and provider counseling associated with postpartum contraceptive use.
View Article and Find Full Text PDFMed Anthropol Q
December 2024
Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Based on 28 months of ethnographic research in Deanuleahki-a river valley in Sápmi, the transborder Indigenous Sámi homeland-this article traces my interlocutors' striving to reclaim and repair ecological and kin relations through the everyday praxis of care. I trace this striving through the unmaking and remaking of local relations of care amidst encroachment by post-Second World War Nordic welfare states and regimes of environmental stewardship. I propose a dual conceptualization of ecosocial injury and resurgent care to account for, on the one hand, care's alienation from its social and ecological contexts; and, on the other, the intimate everyday labor of revivifying relations of kinship and belonging, and conditions of material livability, within local ecologies.
View Article and Find Full Text PDFHealth Res Policy Syst
December 2024
Ontario Network of Sexual Assault/Domestic Violence Treatment Centres, 76 Grenville St, Toronto, ON, M5S 1B2, Canada.
Background: Transgender (trans) people experience high rates of sexual assault (SA) and intimate partner violence (IPV) and seldom receive the care and supports they need post-victimization. However, there is little to no research that aids in the development or improvement of related interventions. We undertook a study to build a novel Canadian research agenda on SA/IPV against trans people to guide future work and address these profound gaps in knowledge.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!