AI Article Synopsis
- - An increase in gonococcal infections has been observed in Europe and Spain, leading to more cases of disseminated gonococcal infection, which can include gonococcal arthritis.
- - Five cases of gonococcal arthritis were reported in a Madrid hospital between October 2022 and October 2023, primarily affecting male patients with a history of unprotected sex.
- - Advances in molecular techniques have improved the identification of culture-negative gonococcal arthritis cases and have revealed mutations linked to fluoroquinolone resistance, prompting a shift towards oral treatments.
Article Abstract
In recent years, there has been an increase in infections in Europe and Spain. Disseminated gonococcal infection is an uncommon clinical presentation that includes gonococcal arthritis. Improved antibiotic treatment has reduced the incidence of gonococcal arthritis. However, the increase in gonococcal infections may have increased the frequency of this clinical entity in recent times. We report five cases of gonococcal arthritis in patients in a tertiary-care hospital in the northern area of Madrid (Spain) from October 2022 to October 2023. Major cases occurred in male patients with unprotected sex and polyarticular symptoms requiring hospital admission and treatment with ceftriaxone and cefixime. The use of molecular techniques has allowed the detection of a greater number of culture-negative cases of gonococcal arthritis, as well as the detection of mutations associated with resistance to fluoroquinolone for switching to oral treatment.
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| http://dx.doi.org/10.1177/09564624241254877 | DOI Listing |
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