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Effects of Ab501 (certolizumab mice equivalent) in arthritis induced bone loss.
ARP Rheumatol
January 2024
Instituto de Medicina Molecular-João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Centro Académico de Medicina de Lisboa, Portugal.
Introduction - Rheumatoid arthritis (RA) is a chronic immune-mediated inflammatory disease, which causes local and systemic bone damage. The main goal of this work was to analyze, how treatment intervention with Ab501 (certolizumab mice equivalent) prevents the disturbances on bone structure and mechanics induced by arthritis. Methods - Thirty DBA/1 collagen-induced arthritis (CIA) mice were randomly housed in experimental groups, as follows: arthritic untreated (N=9), preventive intervention (N=10) and treatment intervention (N=11).
View Article and Find Full Text PDFCerebellar hemorrhage in neonates: pattern analysis by ultrasonography and magnetic resonance imaging.
Pediatr Radiol
January 2025
Department of Radiology, Korea University Ansan Hospital, Korea University College of Medicine, Ansan, Republic of Korea.
Background: Cerebellar hemorrhage in neonates is increasingly being identified but is still underdiagnosed. While magnetic resonance imaging (MRI) is the optimal imaging modality for cerebellar hemorrhage evaluation, ultrasonography (US) is commonly used for screening. Characterizing the patterns and distribution of cerebellar hemorrhage lesions can help facilitate its detection by aiding to focus on prevailing type of cerebellar hemorrhage.
View Article and Find Full Text PDFSustainable improvement of granite sludge dust properties using microbially induced carbonate precipitation (MICP): strength enhancement, erosion prevention, and dust mitigation.
Environ Sci Pollut Res Int
January 2025
Department of Civil Engineering, National Institute of Technology Warangal, Warangal, 506004, India.
Granite sludge dust (GSD), a significant byproduct of granite processing globally, poses severe environmental and public health challenges, with India alone generating 200 million tons annually. The conventional use of GSD in soil stabilization and construction materials is limited to 20-30%, underscoring the urgent need for sustainable repurposing solutions within the circular economy catering to broader bulk utilization. Unlike traditional techniques, repurposing granite dust using microbially induced calcite precipitation (MICP) offers a sustainable low-impact and eco-friendly ground improvement solution.
View Article and Find Full Text PDFDoping in Combat Sports: a systematic review.
Phys Sportsmed
January 2025
Faculty of Sport and Physical Education, University of Novi Sad, Novi Sad, Serbia.
Purpose: This systematic review aims to synthesize the current research on doping in combat sports, examining the prevalence, detection methods, prevention strategies, and overall impact on combat sports.
Design/methodology/approach: Of the 21 identified articles, six met the inclusion criteria. A systematic approach was used, including content analysis based on specific criteria: articles in English, original research, and relevance to sport and doping.
Natural Products From Plants Targeting Leptin Resistance for the Future Development of Anti-Obesity Agents.
Phytother Res
January 2025
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.
Obesity is a serious health threat, which has affected 16% of adults globally in 2022 and shows a trend toward youthfulness. Leptin, as a regulator of body weight, can suppress appetite and promote energy expenditure, making it potential in obesity treatment. Nevertheless, with the progress of relevant research, it is worth noting that monotherapy with leptin is not an effective strategy since most obese individuals are hyperleptinemic and resistant to leptin, where high levels of leptin fail to exert its weight-loss effects.
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