AI Article Synopsis

  • Post-transplant lymphoproliferative disorders are serious complications that can occur after organ transplants, often leading to high mortality rates and difficulty in diagnosis.
  • A case study involved a renal transplant patient with unexplained soft-tissue nodules, which were further investigated through a puncture biopsy.
  • The biopsy confirmed the presence of post-transplant lymphoproliferative disease, specifically identifying it as a diffuse large B-cell lymphoma, highlighting the need for aggressive diagnostic measures in such cases.

Article Abstract

Background: Post-transplant lymphoproliferative disorders are characterized by atypical clinical manifestations, high mortality, and missed diagnosis rates.

Methods: We report a case of renal transplantation in a patient with unexplained soft-tissue nodular shadows, and the type of the post-transplant abnormal soft-tissue shadows was clarified by puncture biopsy.

Results: The pathologic returns were consistent with the post-transplant lymphoproliferative disease, and the immunohistochemical returns supported a diffuse large B-cell lymphoma (non-growth center origin).

Conclusions: In organ transplant patients, when unexplained soft tissue nodular shadows are present, the possibility of post-transplant lymphoproliferative disorders should be considered, and an aggressive puncture biopsy should be performed to clarify the diagnosis.

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http://dx.doi.org/10.7754/Clin.Lab.2023.231140DOI Listing

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