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Effects of Drought Stress at the Booting Stage on Leaf Physiological Characteristics and Yield of Rice.
Plants (Basel)
December 2024
Hubei Key Laboratory of Food Crop Germplasm and Genetic Improvement, Institute of Food Crops, Hubei Academy of Agricultural Sciences, Wuhan 430064, China.
Drought stress is a major environmental constraint that limits rice ( L.) production worldwide. In this study, we investigated the effects of drought stress at the booting stage on rice leaf physiological characteristics and yield.
View Article and Find Full Text PDFResearch Progress of Liquid Biopsy Based on DNA Methylation in Tumor Diagnosis and Treatment.
Biomolecules
December 2024
Department of Clinical Laboratory Medicine, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.
Liquid biopsy has been gradually applied to the clinical diagnosis and treatment of tumors because of its non-invasive and real-time reflection of the tumor status, as well as the convenience of sample collection, which allows the detection of primary or metastatic malignant tumors and reflects the heterogeneity of the tumors. DNA methylation, which is a type of epigenetic modification, is essential in the progression of tumors. This review introduces the common DNA methylation analysis methods and discusses their advantages and disadvantages, focusing on the new progress of DNA methylation-based liquid biopsy in tumor diagnosis and treatment.
View Article and Find Full Text PDFFe/Mo-Based Lipid Peroxidation Nanoamplifier Combined with Adenosine Immunometabolism Regulation to Augment Anti-Breast Cancer Immunity.
Adv Mater
January 2025
Nurturing Center of Jiangsu Province for State Laboratory of AI Imaging & Interventional Radiology (Southeast University), Department of Radiology, Zhongda Hospital, Medical School, Southeast University, 87 DingJiaQiao Road, Nanjing, 210009, P. R. China.
Immunogenic cell death (ICD)-mediated immunization strategies have great potential against breast cancer. However, traditional strategies neglect the increase in the immunosuppressive metabolite, adenosine (ADO), during ICD, leading to insufficient therapeutic outcomes. In this study, it is found that the adenosine A2A receptor (A2AR) is significantly expressed in breast cancer and positively associated with regulatory T (Treg) cells.
View Article and Find Full Text PDFPregnancy and Nursing Management for Embryo-Transferred and Genetically Modified Rabbits.
J Vis Exp
December 2024
Guangdong Medical Laboratory Animal Center, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University;
With the advancement of scientific research, the demand for gene-edited rabbit models is increasing. However, there are limited pregnancy and feeding management systems for gene-edited rabbits, leading to low survival rates among gene-edited rabbits prepared by many inexperienced researchers. Therefore, proper guidance is essential.
View Article and Find Full Text PDFOcean's largest chlorophyll-rich tongue is extending westward (2002-2022).
Nat Commun
January 2025
State Key Laboratory of Marine Environmental Science, College of Ocean and Earth Sciences, Xiamen University, Xiamen, Fujian, 361102, China.
Upwelling in the Equatorial Pacific nurtures an expansive, westward-stretching chlorophyll-rich tongue (CRT), supporting 18% of the annual global new production. Surrounding the CRT are the oligotrophic subtropical gyres to the north and south, which are suggested to be expanding under global warming. Yet, how this productive CRT has changed, expanding or contracting, remains unknown.
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