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FIGO 2023 - too soon or just in time? Evolution or a revolution? Review of the newest endometrial cancer staging classification.
Ginekol Pol
November 2024
Department of Gynecological Surgery and Gynecological Oncology of Adults and Adolescents, Pomeranian Medical University, Szczecin, Poland.
The FIGO staging system is an integral part of the therapeutic and treatment process in female genital tumors. It cements the knowledge gained to date to plan patient treatment prognosis and the course of the disease and compare treatment outcomes between centers in the most individualized yet systematic way. In response to these assumptions, the FIGO Committee on Gynaecological Oncology updated the endometrial cancer staging classification in June 2023.
View Article and Find Full Text PDFIs 26S proteasome non-ATPase regulatory subunit 6 a potential molecular target for intrahepatic cholangiocarcinoma?
World J Hepatol
November 2024
Hepatosplenic Surgery Center, The First Affiliated Hospital of Harbin Medical University, Harbin 150001, Heilongjiang Province, China.
Article Synopsis
- The article discusses the challenges of treating intrahepatic cholangiocarcinoma (iCCA), as most patients do not respond well to existing therapies and highlights ongoing efforts to find new molecular targets.
- It focuses on a study by Tang which examines the role of the PSMD6 gene in iCCA cells, finding it crucial for cell proliferation and overexpressed in iCCA tissues, although the study has limitations regarding its methods and insights into mechanisms.
- The editorial also mentions recent advancements in targeted drug therapies and immunotherapies for iCCA, and underscores the potential of CRISPR technology and other computational methods in cancer research.
Unveiling the clinicopathological enigma of crawling-type gastric adenocarcinoma.
World J Gastrointest Oncol
November 2024
Department of General Surgery, University Hospital of Larissa, University of Thessaly, Biopolis Campus, Larissa 41110, Greece.
In this editorial we comment on the article by Xu . Gastric adenocarcinoma (GA) is a malignancy which arises from the gastric mucosa and encompasses heterogenous tumors with varying characteristics. There are two main classifications: Lauren's and the World Health Organization distinguishing the diverse types of GA depending on clinical, genetic, morphological and epidemiological features.
View Article and Find Full Text PDFMinimal Access vs Conventional Nipple-Sparing Mastectomy.
JAMA Surg
October 2024
Department of Surgery, School of Medicine, Kyungpook National University, Kyungpook National University Chilgok Hospital, Daegu, Republic of Korea.
Importance: While nipple-sparing mastectomy (NSM) for breast cancer was only performed using the open method in the past, its frequency using endoscopic and robotic surgical instruments has been increasing rapidly. However, there are limited studies regarding postoperative complications and the benefits and drawbacks of minimal access NSM (M-NSM) compared with conventional NSM (C-NSM).
Objective: To examine the differences in postoperative complications between C-NSM and M-NSM.
Neonatal autopsy-is it relevant in today's era?
J Trop Pediatr
July 2024
Department of Pathology and Laboratory Medicine, All India Institute of Medical Sciences, Bhubaneswar, India.
Autopsy of infants can provide vital information about the cause of death and contributes to the detection of diagnostic errors, especially in a low- or middle-income country. To observe the clinicopathological agreement in neonatal deaths in neonatal intensive care units (NICU) and comment on the additional information retrieved by autopsy. A retrospective observational study was conducted in the NICU from January 2020 to December 2022.
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