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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11280639 | PMC |
| http://dx.doi.org/10.46747/cfp.7005322 | DOI Listing |
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Alzheimers Dement
December 2024
Indiana University School of Medicine, Indianapolis, IN, USA.
Background: Focusing on novel AD treatments, the TREAT-AD centers offer an array of free research tools, shared via the AD Knowledge Portal in a Target Enablement Package (TEP). This abstract showcases the research conducted by the IUSM-Purdue TREAT-AD Center, specifically focusing on Targeting class-II PI3K's as a potential breakthrough in AD therapy. Endocytosis within the brain encompasses diverse pathways for internalizing extracellular cargoes and receptors into cells.
View Article and Find Full Text PDFMachine Learning-Assisted Prediction of Photothermal Metal-Phenolic Networks.
Angew Chem Int Ed Engl
January 2025
Stomatological Hospital of Chongqing Medical University, 426 SONGSHI NORTH RAOD, YUBEI DISTRICT, 401147, chongqing, CHINA.
Photothermal therapy (PTT) demonstrates significant potential in cancer treatment, wound healing, and antibacterial therapy, with its efficacy largely depending on the performance of photothermal agents (PTAs). Metal-phenolic network (MPN) materials are ideal PTA candidates due to their low cost, good biocompatibility and excellent ligand-to-metal charge transfer properties. However, not all MPNs exhibit significant photothermal properties, and the vast chemical space of MPNs (over 700,000 potential combinations) complicates the screening of high-photothermal materials.
View Article and Find Full Text PDFChanging or validating physician opioid prescribing behaviors through audit and feedback and academic detailing interventions in primary care.
Implement Res Pract
January 2025
Institute for Health System Solutions and Virtual Care, Women's College Research and Innovation Institute, Women's College Hospital, Toronto, ON, Canada.
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In-silico-based lead optimization of hit compounds targeting mitotic kinesin Eg5 for cancer management.
In Silico Pharmacol
January 2025
Phyto-medicine and Computational Biology Laboratory, Department of Biochemistry, Adekunle Ajasin University, Akungba-Akoko, Ondo State Nigeria.
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View Article and Find Full Text PDFDiagnostic efficacy of dual-energy CT virtual non-calcium technique in the diagnosis of bone marrow edema of sacroiliac joints in ankylosing spondylitis.
J Orthop Surg Res
January 2025
Medical school, Kunming University of Science and Technology, Kunming, Yunnan, China.
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