The new analogues of --bergamotene from endophytic fungus sp. E121 with yam culture medium.

Two new bicyclic sesquiterpenes,Δ-2, 5, 11-trihydroxyl--cis-bergamotene () and Nigrohydroin A (), together with ten known compounds ( and -) were obtained from endophytic fungus sp. E121. The structures were elucidated on the basis of their 1D and 2D NMR spectra and mass spectrometric data. The possible biosynthetic pathway of compounds , , and in sp. E121were reported according to literature. The phytotoxic assay results indicated that the acetyl fragment in α-acetylorcinol may contribute to the phytotoxic activity of this compound.