[Peripheral Nerve and Muscle Disorders Associated with Sjögren's Syndrome].

Brain Nerve

Department of Neurology and Neurological Science, Graduate School, Tokyo Medical and Dental University(TMDU).

Published: May 2024

Sjögren's syndrome is often accompanied by various neurological complications, among which peripheral neuropathy is the most common. A variety of clinical phenotypes of peripheral neuropathy, including axonal polyneuropathy and sensory ataxic neuropathy are reported in the literature. We present an overview of the pathophysiology and differential diagnosis of each phenotype. Immunotherapy using corticosteroids and high-dose intravenous immunoglobulin therapy tends to elicit varied therapeutic responses depending on the peripheral neuropathy phenotype. We also discuss myositis, a possible complication of Sjögren's syndrome.

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Source
http://dx.doi.org/10.11477/mf.1416202648DOI Listing

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