Purpose Of Review: To highlight novel findings in the detection of monosodium urate deposits in vessels using dual energy computed tomography, and to discuss the potential clinical implications for gout and hyperuricemia patients.
Recent Findings: Gout is an independent risk factor for cardiovascular disease. However, classical risk calculators do not take into account these hazards, and parameters to identify patients at risk are lacking. Monosodium urate measured by dual energy computed tomography is a well-established technology for the detection and quantification of monosodium urate deposits in peripheral joints and tendons. Recent findings also suggest its applicability to identify vascular urate deposits. Dual energy computed tomography is a promising tool for detection of cardiovascular monosodium urate deposits in gout patients, to better delineate individuals at increased risk for cardiovascular disease.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11224090 | PMC |
| http://dx.doi.org/10.1007/s11926-024-01151-y | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Clinical consequence of hypophosphatemia during antiviral therapy for chronic hepatitis B.
Kidney Res Clin Pract
January 2025
Division of Nephrology, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Background: Antiviral therapy is an essential treatment for chronic hepatitis B (CHB) infection. Although hypophosphatemia is an important adverse effect of antiviral agents, its clinical significance remains unclear. We investigated the incidence and clinical consequences of hypophosphatemia in a large cohort of CHB patients.
View Article and Find Full Text PDFThe value of growth differentiation factor 15 as a biomarker for peripheral artery disease in diabetes patients.
Diabetol Metab Syndr
January 2025
Kaohsiung Veterans General Hospital, Kaohsiung City, Taiwan.
Background: Growth differentiation factor 15 (GDF15) is significantly correlated with glycolipid metabolic disorders. Increased GDF15 levels are associated with obesity, insulin resistance, and diabetes as well as a poorer diabetes progression and prognosis. This is a prospective cohort study investigated the association between circulating GDF15 and diabetic peripheral artery disease.
View Article and Find Full Text PDFSex-based disparities in the association between uric acid levels and anxiety: a cross-sectional analysis of nationwide data in Korea.
BMC Psychiatry
January 2025
Department of Psychiatry and Institute of Behavioral Science in Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
Background: Uric acid has antioxidant properties, and several studies have suggested its neuroprotective effects. Despite reports of increased oxidative damage and decreased antioxidants in anxiety disorders, findings remain inconclusive. This study investigated the association between serum uric acid levels and anxiety symptoms, stratified by sex, using nationwide data from South Korea.
View Article and Find Full Text PDFTaurine alleviates dysfunction of cholesterol metabolism under hyperuricemia by inhibiting A2AR-SREBP-2/CREB/HMGCR axis.
J Lipid Res
January 2025
State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Jinghai District, Tianjin, China; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:
Dysfunctional cholesterol metabolism is highly prevalent in patients with hyperuricemia. Both uric acid and cholesterol are independent risk factors for atherosclerosis, contributing to an increased incidence of cardiovascular disease in hyperuricemia. Investigating the pathological mechanisms underlying cholesterol metabolism dysfunction in hyperuricemia is essential.
View Article and Find Full Text PDFResearch note: Protective effects of compound mycotoxin detoxifier in broiler chicken fed aflatoxins-contaminated diets.
Poult Sci
January 2025
Department of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, PO Box 14115-336, Iran. Electronic address:
This study was planned and executed to investigate the effects of two levels of compound toxin binder (CTB) on growth performance, serum biochemistry, antioxidant status, intestinal morphology, and the ileal selected microflora population in broiler chickens. A total of 240 one-day-old Ross 308 broiler chickens were divided into four treatments and six replicates (10 chickens per replicate). Experimental groups included; 1, negative control (NC; no aflatoxins (AFs) and no additives); 2, positive control (PC; 490 µg/kg AFs); 3, low levels of compound toxin binder (LCTB), PC + 1 g/kg available CTB (Navacidox); and 4, high levels of compound toxin binder (HCTB), PC + 2 g/kg Navacidox.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!