A patient who received a loop sigmoid colostomy was diagnosed with ulcerative colitis (pancolitis type) and treated with infliximab. Thereafter, he relapsed with intestinal inflammation only on the rectal side of the loop sigmoid colostomy and not on the oral side. Autologous fecal microbiota transplantation from the proximal intestine to the distal intestine was performed to treat the inflammation but was ineffective. He was treated with oral prednisolone and induced into remission. After analyzing fecal samples from the patient, we observed an alteration of the composition of the intestinal microbiota with intestinal inflammation, including a reduction of phylum Firmicutes in the inflamed distal intestine, whereas Firmicutes was conserved in the proximal non-inflamed intestine and recovered in the distal intestine after induction of remission. Thus, our results indicated that the inflammation was associated with an alteration of the intestinal microbiota.
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http://dx.doi.org/10.7759/cureus.57941 | DOI Listing |
ACS Omega
November 2024
Department of Instrumentation and Control Engineering, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal 576 104, Karnataka,India.
Batch reactors are type of chemical reactors, where the reactants are loaded to process for a defined batch time and the products are removed after the polymerization reaction completion. Specialty chemicals and food processing industries widely use BRs due to their versatility and suitability for handling small- to medium-scale production, complex reactions, and varying reaction conditions. This article employs a CNN-LSTM-based nonlinear model predictive controller (NMPC) to effectively track the temperature profile of a BR.
View Article and Find Full Text PDFCureus
October 2024
Surgery, Bakersfield Memorial, Bakersfield, USA.
Cureus
October 2024
Acute Care Surgery, Hamad Medical Corporation, Doha, QAT.
The COVID-19 pandemic has primarily been characterized by respiratory symptoms, but emerging evidence suggests multi-organ involvement, including the gastrointestinal tract. This case report aims to highlight colon perforation as a rare but significant complication in COVID-19 patients. We present two cases of male patients, aged 38 and 33, who were admitted with severe COVID-19 symptoms and required intubation and ventilator support.
View Article and Find Full Text PDFSci Rep
September 2024
Department of Computer Science, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Clin Endosc
November 2024
Division of Gastroenterology, Department of Internal Medicine, Yeouido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Background/aims: Colonic stenting plays a vital role in the management of acute malignant colonic obstruction. The increasing use of self-expandable metal stents (SEMS) and the diverse challenges posed by colonic obstruction at various locations underscore the importance of effective training for colonic stent placement.
Methods: All the components of the simulator were manufactured using silicone molding techniques in conjunction with three-dimensional (3D) printing.
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