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Fatal borealpox in an immunosuppressed patient treated with antivirals and vaccinia immunoglobulin - Alaska, 2023.
Clin Infect Dis
November 2024
Section of Epidemiology, Alaska Division of Public Health, Anchorage, Alaska, USA.
Background: Borealpox virus (BRPV, formerly known as Alaskapox virus) is a zoonotic member of the Orthopoxvirus genus first identified in a person in 2015. In the six patients with infection previously observed BRPV involved mild, self-limiting illness. We report the first fatal BRPV infection in an immunosuppressed patient.
View Article and Find Full Text PDFWhat the pox? Review of poxviruses affecting humans.
J Clin Virol
October 2024
Quest Diagnostics, 33608 Ortega Highway. San Juan Capistrano, CA 92675 USA.
Article Synopsis
- The recent outbreaks of human mpox and borealpox, including a reported death, have increased awareness about the Poxviridae family's zoonotic risks.
- This review focuses on various poxviruses that impact humans, covering their pathogenesis, epidemiology, and diagnostic techniques.
- Treatment options for poxviruses are not addressed in this review.
Borealpox (Alaskapox) virus: will there be more emerging zoonotic orthopoxviruses?
Lancet Microbe
August 2024
Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, 7925 Cape Town, South Africa. Electronic address:
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