AI Article Synopsis
- Postoperative sore throat (POST) is a frequent issue after endotracheal tube removal, and this study aimed to see if managing cuff pressure during surgery could reduce its occurrence in gynecological laparoscopic patients.
- In a trial involving 60 patients, one group had their cuff pressure actively adjusted, while the control group only had it monitored, with results showing significantly less POST in the actively managed group (3.3% vs. 26.7%).
- Though the CPMA group had fewer sore throats, they experienced more postoperative nausea and vomiting, and no notable differences were found in cough, hoarseness, or pain levels between the groups.
Article Abstract
Background: Postoperative sore throat (POST) is a common complication following endotracheal tube removal, and effective preventive strategies remain elusive. This trial aimed to determine whether actively regulating intraoperative cuff pressure below the tracheal capillary perfusion pressure threshold could effectively reduce POST incidence in patients undergoing gynecological laparoscopic procedures.
Methods: This single-center, randomized controlled superiority trial allocated 60 patients scheduled for elective gynecological laparoscopic procedures into two groups: one designated for cuff pressure measurement and adjustment (CPMA) group, and a control group where only cuff pressure measurement was conducted without any subsequent adjustments. The primary outcome was POST incidence at rest within 24 h post-extubation. Secondary outcomes included cough, hoarseness, postoperative nausea and vomiting (PONV) incidence, and post-extubation pain severity.
Results: The incidence of sore throat at rest within 24 h after extubation in the CPMA group was lower than in the control group, meeting the criteria for statistically significant superiority based on a one-sided test (3.3% vs. 26.7%, P < 0.025). No statistically significant differences were observed in cough, hoarseness, or pain scores within 24 h post-extubation between the two groups. However, the CPMA group had a higher incidence of PONV compared to the control group. Additionally, the control group reported higher sore throat severity scores within 24 h post-extubation.
Conclusions: Continuous monitoring and maintenance of tracheal tube cuff pressure at 18 mmHg were superior to merely monitoring without adjustment, effectively reducing the incidence of POST during quiet within 24 h after tracheal tube removal in gynecological laparoscopic surgery patients.
Trial Registration: The study was registered at www.chictr.org.cn (ChiCTR2200064792) on 18/10/2022.
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Source |
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| http://dx.doi.org/10.1007/s10877-024-01173-y | DOI Listing |
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