Cholesteatoma is a lesion capable of destroying surrounding tissues, which may result in significant complications. Surgical resection is the only effective treatment; however, the presence of cholesteatoma recidivism is common. This study evaluated the effectiveness of the Attic Exposure-Antrum Exclusion (AE-AE) surgical technique in treating cholesteatomas and identifying factors associated with recidivism. Additionally, the study aimed to assess the utility of non-echo-planar diffusion MRI (non-EPI-DWI MRI) in detecting cholesteatoma recidivism in patients undergoing AE-AE surgery. The study involved 63 patients who underwent AE-AE surgery for primary acquired cholesteatoma and were followed up clinically and radiologically for at least five years. The radiological follow-up included a non-EPI-DWI MRI. Results showed that the AE-AE technique successfully treated cholesteatomas, with a recidivism rate of 5.2%. The study also found that non-EPI-DWI MRI was a useful diagnostic tool for detecting cholesteatoma recidivism, although false positives could occur due to the technique's high sensitivity. As Preoperative Pure-tone average (PTA) increases, there is a higher probability of cholesteatoma recidivism in imaging tests ( = 0.003). Overall, the study highlights the importance of the AE-AE surgical technique and non-EPI-DWI MRI in managing cholesteatoma recidivism in patients, providing valuable insights into associated risk factors and how to manage recidivism. Non-EPI-DWI MRI can assist in patient selection for revision surgery, reducing unnecessary interventions and associated risks while improving treatment outcomes and patient care.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11084557 | PMC |
http://dx.doi.org/10.3390/jcm13092587 | DOI Listing |
Eur Arch Otorhinolaryngol
November 2024
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zürich, University Zürich, Frauenklinikstrasse 24, 8091, Zürich, Switzerland.
Purpose: Different surgical techniques exist for treating cholesteatoma, such as microscopical or transcanal endoscopic ear surgery (TEES). This study aimed to compare these two techniques, focusing on quality of life.
Methods: This retrospective single-center study included 188 patients with cholesteatoma.
Int J Pediatr Otorhinolaryngol
December 2024
Department of Otolaryngology, University of Minnesota, Minneapolis, MN, USA; HealthPartners Medical Group, St. Paul, MN, USA. Electronic address:
Otolaryngol Head Neck Surg
January 2025
Department of Pediatric Otolaryngology, Head and Neck Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Objective: The objective of the study is to evaluate the outcomes of surgical management options for cholesteatoma using a national database.
Study Design: Database analysis of the Pediatric Health Information System database to identify children undergoing surgical intervention for cholesteatoma from October 2015 to December 2022.
Methods: Patients were categorized by initial surgical modality: tympanoplasty (TM), tympanoplasty with canal wall-up tympanomastoidectomy (TM-CWU), and tympanoplasty with canal wall-down tympanomastoidectomy (TM-CWD).
Otolaryngol Clin North Am
February 2025
Department of Otorhinolaryngology, Perelman School of Medicine at the University of Pennsylvania, 3400 Spruce Street, 5 Ravdin, Philadelphia, PA 19104, USA; Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
Otolaryngol Clin North Am
February 2025
Division of Pediatric Otolaryngology, Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Children's Health Dallas, 2001 Inwood Road, Dallas, TX 75390, USA. Electronic address:
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