Traumatic pain is frequently encountered in emergency care and requires immediate analgesia. Unfortunately, most trauma patients report sustained pain upon arrival at and discharge from the Emergency Department. Obtaining intravenous access to administer analgesics can be time-consuming, leading to treatment delay. This review provides an overview of analgesics with both fast onset and parenteral, non-intravenous routes of administration, and also indicates areas where more research is required.
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http://dx.doi.org/10.3390/jcm13092560 | DOI Listing |
J Clin Med
April 2024
Department of Anaesthesiology, Amsterdam UMC, 1105 AZ Amsterdam, The Netherlands.
Traumatic pain is frequently encountered in emergency care and requires immediate analgesia. Unfortunately, most trauma patients report sustained pain upon arrival at and discharge from the Emergency Department. Obtaining intravenous access to administer analgesics can be time-consuming, leading to treatment delay.
View Article and Find Full Text PDFPediatr Pulmonol
December 2021
Department of Pediatric Pulmonology, Faculty of Medicine, Marmara University, Istanbul, Turkey.
Background: Chronic pulmonary infection is the leading cause of mortality and morbidity in patients with cystic fibrosis (CF). The most common pathogens isolated in CF are Staphylococcus aureus (SA) and Pseudomonas aeruginosa (PA). Chronic infection of PA and methicillin-resistant S.
View Article and Find Full Text PDFFront Vet Sci
April 2019
QBiotics Group Ltd, Taringa, QLD, Australia.
Mast cell tumor (MCT) is the most common cutaneous neoplasm in dogs and wide surgical resection is the current first-line treatment. However, recurrence is common and often requires more specialist and expensive therapies. Tigilanol tiglate is a novel small molecule drug delivered by intratumoral injection that is currently under development to provide a new option for treating MCT.
View Article and Find Full Text PDFBMJ Open
April 2017
Centre for Health Services Research, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK.
Objective: Evaluate evidence of the efficacy, safety, acceptability and cost-effectiveness of outpatient parenteral antimicrobial therapy (OPAT) models.
Design: A systematic review.
Data Sources: MEDLINE, EMBASE, CINAHL, Cochrane Library, National Health Service (NHS) Economic Evaluation Database (EED), Research Papers in Economics (RePEc), Tufts Cost-Effectiveness Analysis (CEA) Registry, Health Business Elite, Health Information Management Consortium (HMIC), Web of Science Proceedings, International Pharmaceutical Abstracts, British Society for Antimicrobial Chemotherapy website.
Background: The role of iatrogenic transmission within the HIV/AIDS pandemic remains contentious. Estimates of the risk of HIV transmission from injections and blood transfusions are required to inform appropriate prevention policy.
Objectives: Systematic review and meta-analysis of the literature on HIV-1 infectivity for parenteral transmission and blood transfusion.
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