Electric vehicles (EVs) have emerged as a technology that can replace internal combustion vehicles and reduce greenhouse gas emissions. Therefore, it is necessary to develop novel low-viscosity lubricants that can serve as potential transmission fluids for electric vehicles. Thus, this work analyzes the influence of both SiO and SiO-SA (coated with stearic acid) nanomaterials on the tribological behavior of a paraffinic base oil with an ISO VG viscosity grade of 32 and a 133 viscosity index. A traditional two-step process through ultrasonic agitation was utilized to formulate eight nanolubricants of paraffinic oil + SiO and paraffinic base oil + SiO-SA with nanopowder mass concentrations ranging from 0.15 wt% to 0.60 wt%. Visual control was utilized to investigate the stability of the nanolubricants. An experimental study of different properties (viscosity, viscosity index, density, friction coefficient, and wear) was performed. Friction analyses were carried out in pure sliding contacts at 393.15 K, and a 3D optical profilometer was used to quantify the wear. The friction results showed that, for the SiO-SA nanolubricants, the friction coefficients were much lower than those obtained with the neat paraffinic base oil. The optimal nanoparticle mass concentration was 0.60 wt% SiO-SA, with which the friction coefficient decreased by around 43%. Regarding wear, the greatest decreases in width, depth, and area were also found with the addition of 0.60 wt% SiO-SA; thus, reductions of 21, 22, and 54% were obtained, respectively, compared with the neat paraffinic base oil.
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http://dx.doi.org/10.3390/ma17091993 | DOI Listing |
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2024
Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Chongqing Key Laboratory of Pediatrics, Ministry of Education Key Laboratory of Child Development and Disorders, China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing 400014, China.
Objective: To explore the gene mutations of Langerhans cell histiocytosis in children, and to analyze the correlation of mutation with clinical features and prognosis of LCH, so as to provide reference for clinical diagnosis and treatment.
Methods: Fluorescence PCR was used to detect gene mutations in paraffin-embedded tissue samples from 78 children with LCH, and the correlation of mutation with clinical characteristics and prognosis of LCH in children was analyzed.
Results: Among the 78 children, 41 cases (52.
Lab Med
December 2024
Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, United States.
Background: CALR mutation analysis is routinely used to diagnose BCR/ABL1-negative myeloproliferative neoplasms. The 2 most common CALR mutations are a 52-base pair (bp) deletion and a 5-bp insertion, which account for approximately 85% of cases.
Methods: To evaluate our new microfluidic chip assay, we tested CALR mutant and wild-type specimens that were previously analyzed using conventional methods at a reference laboratory.
J Neuroendocrinol
December 2024
Laboratório de Biomedicina do Cérebro, Instituto Estadual do Cérebro Paulo Niemeyer, Secretaria Estadual de Saúde, Rio de Janeiro, Brazil.
Pituitary tumours (PT) are formed in the pituitary gland, a small gland situated at the base of the brain. These tumours can be categorized according to their histological origin and hormone production. In surgical series, non-functioning PT are the commonest subtype, followed by functioning somatotroph and corticotroph tumours.
View Article and Find Full Text PDFMethylome profiling is an emerging clinical tool for tumor classification and liquid biopsies. Here, we developed FLEXseq, a genome-wide methylation profiler that enriches and sequences the fragments of DNA flanking the CCGG motif. FLEXseq strongly correlates (Pearson's r = 0.
View Article and Find Full Text PDFCell Death Dis
November 2024
Department of Gastroenterology, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, China.
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