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This comment discusses the article of Balder and Linden (2022), who debate the existence and role of embitterment in child and adolescent psychopathology. This topic appears highly relevant, but broader literature should be integrated when talking about embitterment. First, we question the conceptualization of embitterment as an emotion.

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Article Synopsis
  • The authors talk about a study that looks at mental health problems and how they are diagnosed in a guide called DSM-5.
  • They focus on breaking down different symptoms and patterns that people with these problems might have.
  • The goal is to understand mental health better and help doctors diagnose patients more accurately.
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Purpose: The "early intervention" paradigm in psychiatry holds significant promise for preventing psychosis. Recent evidence showed that individuals at clinical high risk for psychosis (CHR-P) with antipsychotic (AP) prescription at baseline have higher psychosis transition rates compared with those without AP, although the underlying cause remains unclear. In this article, we reviewed international guidelines on early intervention in CHR-P people, paying specific attention to clinical recommendations on AP treatment.

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Importance: Obesity is associated with numerous psychosocial complications, making psychiatric safety a consideration for treating people with obesity. Few studies have investigated the psychiatric safety of newly available antiobesity medications.

Objective: To evaluate the psychiatric safety of subcutaneous semaglutide, 2.

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