Background: Substantial evidence supports the inverse association between adherence to healthy dietary patterns and frailty risk. However, the role of plant-based diets, particularly their quality, is poorly known.
Objective: To examine the association of two plant-based diets with incidence of physical frailty in middle-aged and older adults.
Design: Prospective cohort.
Setting: United Kingdom.
Subjects: 24,996 individuals aged 40-70 years, followed from 2009-12 to 2019-22.
Methods: Based on at least two 24-h diet assessments, we built two diet indices: (i) the healthful Plant-based Diet Index (hPDI) and (ii) the unhealthful Plant-based Diet Index (uPDI). Incident frailty was defined as developing ≥3 out of 5 of the Fried criteria. We used Cox models to estimate relative risks (RR), and their 95% confidence interval (CI), of incident frailty adjusted for the main potential confounders.
Results: After a median follow-up of 6.72 years, 428 cases of frailty were ascertained. The RR (95% CI) of frailty was 0.62 (0.48-0.80) for the highest versus lowest tertile of the hPDI and 1.61 (1.26-2.05) for the uPDI. The consumption of healthy plant foods was associated with lower frailty risk (RR per serving 0.93 (0.90-0.96)). The hPDI was directly, and the uPDI inversely, associated with higher risk of low physical activity, slow walking speed and weak hand grip, and the uPDI with higher risk of exhaustion.
Conclusions: In British middle-age and older adults, greater adherence to the hPDI was associated with lower risk of frailty, whereas greater adherence to the uPDI was associated with higher risk.
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http://dx.doi.org/10.1093/ageing/afae092 | DOI Listing |
Br J Nutr
January 2025
Division of Nephrology, Department of Internal Medicine, Koc University School of Medicine, Istanbul, Turkey.
This interventional single-center prospective open-label study aims to evaluate the effects of a vegan diet, compared to a vegetarian and omnivorous diet, on metabolic parameters, insulin sensitivity, and liver and kidney steatosis in healthy adults. The study included 53 omnivorous participants aged 18-40 years, body-mass index 18-30 kg/m2, without any chronic disease, chronic medication use, active smoking, or significant alcohol consumption. All participants were omnivorous at baseline and selected to continue an omnivorous diet or transition to a vegetarian or vegan diet, with follow-up over six months.
View Article and Find Full Text PDFAppetite
January 2025
Department of Family Relations and Applied Nutrition, University of Guelph, Guelph, Canada. Electronic address:
The primary objective of this research was to evaluate the feasibility and acceptability of "Supper Heroes", a superhero-themed mobile health (mHealth) intervention designed to reduce food waste and increase plant-based protein food intake among families with children aged 9-14 in Ontario, Canada. A single arm, pre-post mixed methods design was used to evaluate the intervention. The 4-month mHealth intervention included 7 online modules with infographics, videos, and activities to help families reduce their food waste and eat more plant-based protein foods.
View Article and Find Full Text PDFNutr Rev
December 2024
Department of Nutrition and Dietetics, Kent University, 34406 İstanbul, Türkiye.
Context: Rheumatoid arthritis (RA) is an autoimmune disease that leads to chronic inflammation and joint damage. Various plant-based diets are thought to have effects on RA symptoms and disease activity.
Objective: Relevant literature on the effect of different types of plant-based diets on RA was reviewed.
Alzheimers Dement
December 2024
Macquarie University, Sydney, NSW, Australia
Background: Interest and consumption of plant‐based diets (PBD) in the 21 century continued to increase, particularly in western societies, with the perception that PBDs are associated with beneficial health outcomes and a reduced environmental footprint. Evidence suggests that PBDs may be protective against neurodegenerative diseases, such as Alzheimer’s disease (AD). Health effects of PBDs such as reduction of inflammation, shift in gut microbiota composition, reduced risk of type 2 diabetes and cardiovascular disease are all believed to attribute to reduced AD risk.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Montefiore Einstein, Bronx, NY, USA
Background: A meta‐analysis of over 2.3 million individuals in 14 studies showed that individuals with type II diabetes (T2DM) are at a 60% increased risk for development of any dementia compared to those without T2DM. A Whole Food, Plant Based dietary (WFPB) pattern has been associated with lower blood glucose levels and decreased insulin requirements.
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