AI Article Synopsis
- Macrocyclization reactions are important methods for creating organic molecules with specific 3D shapes, known as stereogenic centers, which are vital for their functions.
- Recent advancements in this area focus on synthesizing natural products and their analogues by using strategies inspired by nature as well as those that are not.
- The summary categorizes various examples of these synthesis techniques based on how they achieve asymmetry, meaning they create molecules that are not mirror images of themselves.
Article Abstract
Macrocyclization reactions that are capable of stereoselectively co-creating one or more stereogenic centers have become useful strategies for the effective syntheses of structurally and functionally diverse organic molecules. This JOCSynopsis summarizes the recent progress in the field of natural product and analogue syntheses, including both bioinspired and non-bioinspired macrocyclic disconnections. Selected examples are organized on the basis of the sources of the asymmetric inductions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.joc.4c00030 | DOI Listing |
Publication Analysis
Top Keywords
exploring non-comfort
4
non-comfort zone
4
zone central
4
central chirality-generating
4
chirality-generating macrocyclizations
4
macrocyclizations macrocyclization
4
macrocyclization reactions
4
reactions capable
4
capable stereoselectively
4
stereoselectively co-creating
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!