AI Article Synopsis
- This study analyzed data from 107 brain glioma patients to evaluate how sodium fluorescein-guided microsurgery affects cognitive function and short-term recovery.
- The research group showed better outcomes, such as shorter surgery time, less blood loss, and improved cognitive scores compared to the control group which had routine surgery.
- The findings suggest that while both groups had similar complication rates, the use of sodium fluorescein may enhance patients' quality of life and cognitive abilities without sacrificing long-term survival.
Article Abstract
This study conducted a retrospective analysis on 107 brain glioma patients treated from January 2018 to February 2020 to assess the impact of sodium fluorescein-guided microsurgery on postoperative cognitive function and short-term outcomes. Patients were divided into two groups: a control group (n=50 patients) undergoing routine surgery and a research group (n=57 patients) receiving sodium fluorescein-guided microsurgery. The study compared postoperative total resection rates, changes in cognitive scores, and neuropeptide levels in cerebrospinal fluid between the groups. The findings revealed that the research group experienced shorter surgical time and hospitalization duration, reduced blood loss, and higher total resection rates compared to the control group. Furthermore, the research group demonstrated improvements in cognitive scores and an increase in neuropeptide levels after surgery. There was no significant difference in the comparison of the incidence of postoperative complications between the two groups. The WHO classification and preoperative performance scores were independent prognostic factors for the evaluation of 3-year survival, highlighting the clinical significance of sodium fluorescein-guided microsurgery in improving quality of life and cognitive functions of patients without compromising their long-term survival outcomes.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076256 | PMC |
| http://dx.doi.org/10.62347/WFSK7541 | DOI Listing |
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