Subpopulation analysis of immunocompetent cells of peripheral blood was performed in 286 patients with bronchopulmonary diseases (acute and protracted pneumonia, chronic obstructive and non-obstructive bronchitis). All the examined manifested the presence of secondary immune deficiency of different nature. The authors describe the results of immunomodulatory therapy with levamisole, diuciphon, zixorin, catergen and prodigiosan. Discuss in detail possible causes of the development of immune deficiencies and the mechanisms of action of the immunomodulators.

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