AI Article Synopsis
- The study aimed to compare positive pressure (PP) and negative pressure (NP) methods for reducing gas in biological tissues to improve acoustic imaging.
- The results showed that PP significantly reduced gas inclusions in porcine liver samples, while NP had little effect and could even increase gas levels.
- The conclusion suggests that PP is a more effective and reliable method for tissue degassing, while NP may not be suitable for this purpose.
Article Abstract
Objective: To compare the effectiveness of positive pressure (PP) and negative pressure (NP) for reducing gas inclusions in biological tissues in preparation for acoustic imaging.
Methods: Eighteen pieces of porcine liver in degassed saline were included in this study. For the PP group (n = 9 samples), a wristwatch waterproof tester was used to pressurize samples to 0.41 MPa (59 psi) for 10 min. For the NP group (n = 9 samples), a desiccator at -0.08 MPa (-12 psi) was used for 30 min. Backscatter coefficients (BSCs) were calculated over the central frequency range of the backscattered spectra and paired-samples t-tests were performed.
Results: Utilization of PP resulted in a decrease in BSC for all samples, indicating less gas post-PP (pre-PP -13.0 ± 4.3 dB [mean ± SD], post-PP -18.9 ± 5.0 dB, p = .001). Utilization of NP resulted in an increase in BSC for the majority of samples (pre-NP -14.6 ± 6.0 dB, post-NP -13.1 ± 5.3 dB, p = .177).
Conclusion: Utilization of a simple PP chamber consistently resulted in a decrease in tissue gas, at lower pressures than previously reported. The vacuum method is ineffective, may result in a paradoxical increase in tissue gas, and may not be recommended for tissue degassing.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11189725 | PMC |
| http://dx.doi.org/10.1016/j.ultrasmedbio.2024.04.004 | DOI Listing |
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